Clinical Observation Of Tongluo Decoction In Treatment Of Pelvic Inflammatory Disease Sequelae And Its Influence On IL-2,MCP-1,D-D And Uterine Artery Blood Flow

Objective To observe the clinical effect of Tongluo decoction in the treatment of pelvic inflammatory disease sequelae of cold coagulation and blood stasis syndrome,and to observe the effect of this method on IL-2,MCP-1inflammatory factor and DD in chronic pelvic inflammatory disease And to observe its effect on uterine and ovarian blood flow from the perspective of hemodynamics and to explore the mechanism of the treatment of pelvic inflammatory disease,to provide the basis for the promotion of clinical experience.Methods Eighty patients with pelvic inflammatory disease sequelae were randomly divided into two groups: the treatment group(Tongluo decoction +Chrysanthemum morifolium)and the control group 40 cases in the control group(Guizhi Fuling capsule + Chrysanthemum granules enema).The changes of IL-2,MCP-1 expression and D-D,uterine and ovarian artery blood flow were observed before and after treatment.The changes of TCM syndrome,clinical symptoms,signs and comprehensive efficacy were observed before and after treatment.Results The total effective rate was 97.% in the treatment group and 82.5% in the control group,the difference was statistically significant(P <0.05).The total effective rate was 97.4% in the treatment group and 87.5% in the control group,the difference was statistically significant(P <0.05).After treatment,the levels of serum IL-2 and MCP-1 and DD in the two groups decreased,compared with the control group(P <0.05),and the levels of MCP-1 and DD in the treatment group were significantly higher than those in the control group PI and RI decreased in the control group,but no significant difference was found in the control group.The PI of the treatment group and the control group were statistically significant(p <0.01).Conclusion Tongluo Decoction can improve the levels of IL-2,MCP-1 and DD in patients with chronic pelvic inflammatory disease sequelae and cold-blood stasis syndrome,and decrease the level of uterine leiomyoma in a certain degree Ovarian artery blood flow PI,RI,regulate immune function in patients with uterine and ovarian blood flow to improve the efficacy of certain.