Clinical Observation On The Treatment Of Postoperative Patients With Gastric Cancer By Self Regulating Qi And Stomach Decoction Combined With XELOX

Objective:To investigate the clinical efficacy of self regulating qi and stomach soup combined with XELOX in patients with liver stomach disharmony after gastric cancer surgery.Methods:90 patients met the inclusion criteria were randomly divided into the treatment group and the control group,two patients in each group and 45 patients in each group.The control group was given XELOX regimen chemotherapy(capecitabine,1000mg/m2,oral administration of Bid,dl-d14;oxaliplatin,130mg/m2,IV,D1),The treatment group was treated with self regulating qi and stomach soup(300ml,two times orally in the morning or evening)on the basis of the treatment of the control group.The two groups were treated with 21 days as a cycle,and two cycles were treated.The changes of TCM syndrome score,tumor markers,KPS score,toxic reaction and so on were observed.Results:1.After treatment,the scores of TCM syndromes in the two groups were lower than those before treatment,and the difference was statistically significant(P<0.05).2,after treatment,the tumor markers(CEA,CA19-9,CA72-4)of the two groups decreased compared with before treatment,the difference was statistically significant(P<0.05).3.after treatment,the two groups of patients with KPS score compared with before treatment were improved,the difference was statistically significant(P<0.05).Compared with the control group,the KPS score of the treatment group was higher than that of the control group(P<0.05).4,.after treatment,two groups of patients have varying degrees of toxic and side effects.The incidence of WBC,PLT,Hb decrease and digestive tract reaction rate in treatment group were lower than that in control group,the difference was statistically significant(P<0.05):5.The incidence of hand foot syndrome,neurotoxicity and thrombocy-topenia decreased in the treatment group compared with the control group,but the difference was not statistically significant(P>0.05).Conclusion:1.Compared with the simple XELOX regimen,the combination of self regulating qi and stomach soup combined with XELOX regimen can reduce the level of serum tumor markers and improve the clinical efficacy of patients with liver stomach disharmony.2.Compared with the simple XELOX program,the combination of self regulating qi and stomach soup combined with XELOX can improve the clinical symptoms and improve the quality of life of the patients.3.Liqi and stomach could promote the XELOX scheme to improve myelosuppression and relieve digestive reaction.