Font Size: a A A

The Research Of The Cephlosporin’s Skin Test In Economics And The Production Of The Early Clinical Assessment Scale

Posted on:2018-11-24Degree:MasterType:Thesis
Country:ChinaCandidate:L X ZhangFull Text:PDF
GTID:2334330515964386Subject:Clinical Pharmacology
Abstract/Summary:PDF Full Text Request
Background Because cephalosporins are widely used in clinical practice,whether the skin allergic test is currently in clinical debate,but there is no direct evidence at home and abroad to support its skin test.Our hospital cephalosporins use a lot,especially in the surgical ward,and the initial investigation found in our hospital,the hospital departments of the cephalosporin skin test requirements are not the same,some departments using the original skin test,there are Of the department using cefazolin sodium instead of skin test,and some use penicillin instead of skin test,and even some departments do not carry the skin test,and its skin test solution configuration requirements are not the same,the domestic guidelines on cephalosporin skin Test requirements are also different,a variety of cephalosporins skin test requirements are also different,cephalosporin skin test problems we need to pay attention to and the introduction of the corresponding strategy to standardize its management.Objective: 1.To analyse the cephalosporin injection skin test and the cost of the skin test,which provided the basis for the standardized management of cephalosporin skin test to the hospital.2.To develop a early assessment scale table of the cephalosporin drugs skin allergy test is to lay the foundation of the latter dinical application.Methods: 1.The skin test case skin test-related costs and the costs of the cephalosporin allergic reactions had been broken out with the analyzed retrospectively about the 8 kinds of the cephalosporin which commonly used in hospital,and compared the costs of the skin test with the costs of the cephalosporin allergic reactions.2.Basing on preliminary literature research and clinical experience and according to the patient’s own factors and drug factors,and design the questionnaire for using the Delphi method to conduct the questionnnaire survey of 20 experts.Results 1.The positive rate of 100 330 patients who used the eight cephalosporin injections was 6.27%,the direct cost was 3 434 411.72,the indirect cost was 141 985.12 RMB,the cost of medical insurance was 259 096.28 RMB,the cost of the whole society was 3 576 396.84 RMB;The cost of the test was significantly higher than that of the skin allergy test(P <0.05)2.The two experts actively coefficient were 100% and 90.0%,pundits degree were 0.763,and coordination coefficients were 0.56 and 0.617,so the experts’ opinion was convergent,and ultimately determine 13 indicators of the patient’s own,5 indicators of the drug factors.Conclusion 1.As a whole caused enormous economic losses,the cost of the cephalosporin injection skin test was huge and had no economic significance for patients,countries and society.2.The Delphi method applied to the cephalosporin drugs skin allergy test which was scientific and reliable,and lay the foundations for the latter production of the scale.
Keywords/Search Tags:Cephalosporin, Skin Test, Economic Analysis, Anaphylactic Reaction Delphi Method
PDF Full Text Request
Related items