Risk Factors For Perioperative Acute Kidney Injury In Adult Cardiac Valve Surgery With Cardiopulmonary Bypass

Objective:To investigate the incidence and the risk factors of acute kidney injury(AKI)in patients undergoing cardiac valve surgery with cardiopulmonary bypass(CPB)Methods:A retrospective cohort database study was conducted,involving 1349 patients undergoing heart valve surgery with CPB technique.Logistic regression was used to screen out the risk factors of AKI after the surgery.Results:Of the 1349 patients,the incidence of AKI in valve surgery was 28.4%.According to the KIDGO standard in 2012,age(OR=1.05,P<0.001),anemia(OR=1.50,P=0.026),long operation time(OR=1.28,P<0.001),diabetes(OR=2.11,P=0.008),basic serum creatinine(OR=1.01,P=0.0001)plasma transfusion(OR=1.50,P=0.004)during surgery were the independent risk factors for AKI in multivariate logistic regression model.Conclusion:AKI is a common and serious complication following cardiac valve surgery.More attention should be paid to the patients with elder age,anemia,prolonged operation time,diabetes,increased basic serum creatinine and requirement of plasma transfusion during surgery.