Risk Factors Analysis For Peritoneal Dialysis Patients With Diabetic Nephropathy Residual Renal Function Decline

ObjectiveTo observe the impact of peritoneal dialysis patients with diabetic nephropathy residual renal function(RRF)decline by different risk factors.Methods880 cases of continuous ambulatory peritoneal dialysis(CAPD)patients were selected.There were 150 DN and 730 Non-DN patients.The level of HbAlc、CRP、Hb、ALB、BUN、SCr、UCr、UUN and 24h urine volume from the patients was detected.ResultsAfter 12 months’ regular follow-up,RRF level of DN and non-DN group both got significantly decreased(p<0.05).Decent rate of DN group was faster than that of non-DN group(p<0.05).In DN group,decent rate of non-intensive glucose control group(HbA1c>7%)was faster than intensive glucose control group(HbA1c<7%)(p<0.05),while it was similar between intensive glucose control group(HbA1c<7%)and non-DN group(P>0.05).Meanwhile,CRP level in non-intensive glucose control group(HbA1c>7%)of DN group was significantly higher than non-DN group(p<0.05).Conclusion:Diabetic nephropathy peritoneal dialysis patients with intensive glucose control could delay descent rate of RRF better,which might be due to micro-inflammation state on diabetic nephropathy peritoneal dialysis patients.