| PurposeThe purpose of this study was to compare the afficacy of the sonographic features in the BI-RADS lexicon for predicting malignancy grade of invasive ductal breast carcinoma in woman assigned a BI-RADS category of 4 or 5. BI-RADS lexicon includes the lasticity imaging/B-mode ration on strain elastography.MethodsThe radiologists evaluated 283 consecutive case invasive ductal breast carcinoma presenting as a mass in consensus by using the BI-RADS sonographic lexicon. Histologic grade was established on surgical specimens. Agreement was measured with χ2 and Spearman statistics between ultrasonographic signs and the grade of invasive ductal breast carcinoma. The mean elasticity imaging/B-mode ratio of each tumor type was calculated. The elasticity imaging/B-mode ratio of the tumor was compared to the grade of invasive ductal breast carcinoma. A Logistic regression model for predicting the grade of invasive ductal breast carcinoma on the basis of pathology and ultrasonographic criterias was obtained.ResultsThe margins, rear echo characteristics and pathological level has good alignment (χ2= 29.145,62.079, P<0.01). There were differences between Grade III of invasive carcinoma and grade I and II for E/B (P=0.00). And the E/B has good correlation with pathologic level (r=0.519, P= 0.519). There was poor correlation between BI-RADS classification (4a,4b,4c and 5) and invasive carcinoma (χ2= 5.195, P=5.195), neither the BI-RADS classification (4 and 5) (χ2= 2.543, P= 2.543). The mass margin, lesion acoustic sonographic features correlated well with the grade of invasive ductal breast carcinoma by multivariate analysis (OR=50.73、 246.60, P<0.05)ConclusionsMalignancy grade was slightly to moderately predicted by mass margin, lesion acoustic sonographic features and the elasticity imaging/B-mode ration on elastography. Grade Ⅲ of invasive ductal breast cancers were more likely to display abrupt margins, posterior enhancement and larger elasticity imaging/B-mode ration. |
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