| Objective:We evaluated and analyzed operation effects of pharmacy intravenous admixture services(PIVAS) through investigating prescription error detection rate, occupational protection, human resources in staff and other indexes, tested the affects for hospital clinic service quality after PIVAS operation. and provided relevant basis and reference for hospitals that prepare to build PIVAS in China. Methods:Questionnaires were employed to investigate prescription error detection rate, drug management, occupational protection, and human resources allocation of 39 clinical departments that used chemotherapeutic durgs in a month before( September 2012) and after PIVAS(September 2013) implementation, to establish the safety and efficacy evaluation system of PIVAS, and to study the effect of PIVAS implementation on clinical care in pharmacist-nurse combined mode. The data were analyzed through chi-square test, non-paired t test, and Pearson correlation, and p<0.05 was considered as statistically different. Result:1) After PIVAS implemented, prescription error detection rate was significantly increased, from 0.1377% to 0.2043%.2) Before PIVAS implemented, there were many problems in chemotherapy drug management, such as over-base drug storage(30.16%), unclear label(25.40%), expired drug(7.94%), unqualified storage condition(12.70%), mixed storage of multiple drugs(11.11%), inconsistency between the accounts and the drugs(15.87%) and unclear of drug names(9.52%), which were significantly improved after PIVAS implemented.3) Before PIVAS implemented, protection appatus, such as biological safety cabinets, were massively missing, and more than half of nurses did not use them. The use of protective measures in the protective facilities has been significantly impro ved after PIVAS establishment. and the differences were significant in several items.4) Before and after PIVAS implemented, the preparation of chemotherapy drugs cost 90.72±8.06 h and 31.36±2.287 h in total and 0.1008±0 h and 0.036±0 h in average, respectively. The efficacy in all sections was significantly improved, and it was almostly tripled in average.5) Before PIVAS implemented, 16 pharmacists were emplyed, while it was decreased to 5 after PIVAS implemented. Full-time pharmacist was configurated to review prescriptions, which guarenteed the safety of patient thearapy. Conclusion:By comparison, several sections closely related with clinical drug safety, such as prescription error detection rate, chemotherapy drug management, and occupational protection of staffs, were all significantly improved after PIVAS implementation. Besides, human resources in nurse and pharmacist were largely saved. And fully reflected the safety and efficiency for clinical medical work after PIVAS establishment. |
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