The Research On The Efficacy Evaluation Model And System Of Microwave Thermal Ablation Based On Near-infrared

Microwave hyperthermia, as a new type of tumor therapy, has been widely utilized in clinic. It is a kind of hyperthermia with several advantages, such as minimally invasive, painless, large ablation area, and significant treatment. The vital important problem to predict the effects of different dose of microwave in the formulation of the treatment plan is a vital problem. Many studies tried to control the size and shape of ablation region in the microwave ablation. In this paper, we designed an accurate evaluation model of microwave thermal ablation by using finite element simulation software, which could be used to predict the tumor ablation zone before and during the microwave hyperthermia process. To improve the properties of the simulation model in microwave hyperthermia evaluation system, we wrote a microwave thermal ablation temperature field calculation software. Furthermore,we designed a set of microwave hyperthermia evaluation system based on both the near infrared spectroscopy technology and the microwave thermal ablation simulation model.The main contents of this paper as following: 1. We proposed a treatment evaluation scheme of the microwave ablation according to the problems in the microwave ablation technology in clinic; 2.The specific method and procedure of modeling the microwave ablation was investigated. A accurate simulation model used to calculate the electromagnetic field and temperature field by using the dynamic biological thermal physical parameters and electrical parameters was proposed. Then, the model was verified by experiment; 3. A microwave ablation tumor evaluation system was designed,including hardware and software. Hardware part consisted of the microwave thermal ablation system,the real-time temperature acquisition system, and the real time acquisition system of optical parameters. The software part included the function of 3D model, temperature, light parameter data display, and automatic connection of instrument. The temperature field data of simulation model was the fundamental for the prediction of tumor ablation zone.The main contribution of this paper is that we have established the simulation model of microwave needle based on the temperature dependent dynamic tissue parameters. Meanwhile, we use near infrared spectroscopy to monitor the thermal damage degree of tumor during the process of microwave hyperthermia. The results in this paper have the potential for the clinic of tumor treatment.