Clinical Analysis Of Infective Endocarditis

Objective: To summarize the clinical experience of infective endocarditis, and provide reference for the treatment of the disease.Methods: Retrospective analysis of research methods of 31 cases diagnosed in our hospital for infectious endocarditis and accept the epidemiology of surgical treatment of patients, predisposing factors, clinical manifestation, auxiliary examination, echocardiography, blood culture, etc.), treatment and complications of collation and analysis.Results: The group of 31 patients with infective endocarditis in 18 cases of male, female 13 cases; age 4-67(39.90 + 19.29), 15 cases of congenital heart disease including basic heart disease(48.39%)(including 7 cases of ventricular septal defect ventricular septal defect pulmonary valve in 3 cases, 1 cases of ventricular septal defect, 1 cases of ventricular septal defect and three tricuspid valve disease in 1 cases, ruptured sinus of Valsalva aneurysm and 1 cases of ventricular septal defect; ventricular septal defect and aortic double valve lesions in 5 cases, two leaf malformation in 4 cases, aortic valve lesions in 1 cases; 1 cases of double valve; Tetralogy of Fallot congenital ductus arteriosus 1 cases of congenital double outlet right ventricle in 1 cases), 15 cases of valvular heart disease(48.39%)(4 cases, 4 cases of mitral valve disease, aortic valve disease in 4 cases, double valve lesions in 2 cases, three tricuspid valve disease syphilis complicated with aortic valve lesions in 1 cases), 1 cases of prosthetic valve lesions(3.25%).There were 13 cases of Blood culture or vegetations culture were positive, positive rate was 41.94%. Which Streptococcus viridans was 8 cases(61.54%), coagulase negative staphylococci 2 cases(15.38%), group D Streptococcus 1 case(3.25%), Hemophilus Streptococcus 1 case(3.25%), Candida parapsilosis 1 case(3.25%). Preoperative left ventricular end diameter 31~84.2mm, average 53.26 + 11.26 mm, left atrial diameter 21.0~49.9mm, average 35.29 + 7.45 mm.Inciuding all of the patients, 1 case was death in early time(3.25%),The cause of death was multiple organ failure. All the patients were followed up from 3 months to 2 years average 8 months. The loss prevention in 2 cases(6.50%), postoperative left ventricular diastolic end diameter 31~64.1mm, average 44.83 + 6.63 mm, left atrial diameter 17.7~47mm, average 31.22~7.12 mm. follow-up of patients with no late death, recurrence in 2 cases(6.50%), recurrent patients were after regular anti infection treatment cured; paravalvular leakage in 1 case(3.25%), referral Shanghai Ruijin hospital surgery after recovery.Conclusion: 1 Surgical intervention is a safe and effective treatment for infective endocarditis.2. Blood culture or vegetations culture positive cases of infectious endocarditis, Streptococcus and Staphylococcus aureus accounted for proportion in more than 70%, empiric medicine treatment selection antimicrobial spectrum should be covered.3 Organic heart disease is a predisposing factor for infective endocarditis, which is most common in patients with heart valve disease and congenital heart disease.4 Early diagnosis, regular anti infective therapy, and surgical intervention with appropriate timing are critical to the prognosis of patients with infective endocarditis.5 Infective endocarditis involves more than the left heart valve system.