Citizens Died Of Main Factors Affecting The Quality Of Donor Liver Clinical Analysis

Objective: Through to the citizen’s death of main factors affecting the quality of donor liver clinical analysis, provide a reference for clinical selection of donor liver and use, to make limited resources to get more effective clinical application.Methods: Through a retrospective analyzed from July 2011 to November 2011 in four years in our hospital liver and gallbladder surgery of liver transplant surgery the clinical data of 47 patients with end-stage liver disease. Rejecting a history of abdominal surgery or clinical and pathological data is incomplete or abnormal vascular anastomotic postoperative and because the liver factor and dead in three days. Selected cases, according to the receptor 72 h after transplantation, ALT and AST serologic testing results are grouped. Are ideal for liver groups: ALT and AST are less than 1500 u/L; Not-ideal for the liver: ALT and AST is greater than or equal to 1500(or) u/L. To liver transplantation in all kinds of perioperative clinical data using SPSS 22.0 software for statistical processing, and discuss the risk factors affecting the quality of citizens died for liver. Using single factor to compare two kinds of donor liver in the donor’s age, body mass index(BMI), preoperative liver transplantation for the last time the laboratory test results, contains the alanine aminotransferase(ALT), aspartate aminotransferase(AST), total bilirubin(TBIL), direct bilirubin(DBIL), serum creatinine(SCr), urea nitrogen(BUN), international standardization ratio(INR), albumin(propagated), serum sodium(Na), serum potassium(K), alkaline phosphatase(ALP), GGTP(gamma glutamyl transpeptidase)(r- GT), blood glucose, and heat during ischemia time, cold ischemia time, preoperative liver frozen pathological examination results suggest differences such as level of fatty liver. And through the two types of forward stepwise Logistic regression analysis to understand the influence degree of various factors on the quality of DCD for liver, P < 0.05 considering the results have statistical significance.Main Results:1, This study 12 cases with abdominal surgery history or donor information is not complete and ruled out, were included in 35 cases, 31 cases of men,,4 cases of women; Receptor for 7-70- year- old age distribution, the median age of 43.2 years old, donor age distribution for 5-60 years old. 35 cases, 26 cases(74.3%) after transplantation of ALT and AST 72 h after surgery is less than 1500 u/L, donor liver quality evaluation is ideal for liver; 9 cases(25.7%) after transplantation ALT and AST 72 h after surgery(or) greater than or equal to 1500 u/L, the donor liver quality evaluation is not-ideal for the liver.2, Ideal for liver and not-ideal for single factor analysis showed that between two groups on the different levels of liver steatosis statistically significant(P < 0.05). In the two groups in the donor age, BMI, TBil, DBil, Scr, BUN, ALT, AST, ALP, r- GT, propagated, blood glucose, serum sodium, serum potassium, donor INR, warm ischemia time, cold ischemia time and whether the donor liver hepatitis b positive, etc. There was no statistically significant differences.3, Using Logistic regression model to analyze the influence of various factors on the DCD for liver quality results suggest liver fat levels is DCD for of the independent risk factors on the quality of the liver(P < 0.05).Conclusions:1, The level of the hepatic steatosis is the important element of the influence the quality of donor liver.2, Should consider donor preoperative clinical treatment of general situation and the recipients, which will guide for evaluation quality of donor liver and liver allocation.