| Objective : By observing summary analysis of the clinical efficacy of knee osteoarthritis by the treatment of safflower injection knee joint cavity flushing combined with crochet relase, and verify their advantages,observe its long-term curative effect.Methods: Choose the patients from November 2014 to May 2015 visit to Shanxi Hospital of Integrated Traditional and Western Medicine pain management and met the inclusion criteria of knee osteoarthritis, collected 90 cases, aged from 50 to 80 years, and were randomly divided into Saline flush group(group A), safflower injection knee joint cavity flushing group(group B), safflower injection and crochet treatment group(group C)based on patient treatment order and Doll’s random number table method, group A was the control group, group B and group C were the experimental group, 30 cases in each group.Before treatment detailed records of each group according to Lysholm knee score table,knee HSS score, all patients were treated by the above three methods on the condition that they perfecting the related auxiliary examination, and all patients were treated by two times.Patients were followed up for one week and one month after the end of all the treatment,evaluate the efficacy according to Lysholm knee score, HSS score of knee joint. The data of clinical study were analyzed using SPSS 17.0 statistical software, the comparison of multiple sets of samples with full and random data, using single factor analysis of variance(ANOVA), all data were expressed by x ±S, with P<0.05 as a difference, with statistical significance. If the data were in normal distribution, the variance was homogeneous, and the values of each group were statistically significant, and the LSD test was used for multiple comparisons; If the variance is not homogeneous, on the basis of statistical significance, using Tamhanes’ T2 test for multiple comparisons.Results:(1)Three groups in the patient’s age, gender, duration of disease, the number of single and double knee were compared by ANOVA test, P > 0.05, the difference was not statistically significant;(2)Before the treatment, the three groups of patients compared by Lysholm knee score and knee HSS score, by the analysis of variance test, P>0.05, the difference was not statistically significant;(3)The severity of the disease of the three groups patients was compared by ANOVA test before all the treatment, P>0.05, the difference wasnot statistically significant;(4)After 1 weeks and 1 month after the treatment compared with before treatment, according to Lysholm knee score, HSS score of knee joint,the P of three groups were <0.05, the difference was statistically significant;(5) Comparison of the therapeutic effect between the three groups after treatment by 1 week, group A compared with group B by the variance analysis test, P>0.05, the difference was not statistically significant, group A compared with group C, P<0.05, the difference was statistically significant,group B compared with the groupC, P<0.05, the difference was statistically significant;(6)After all the treatment 1 month later, the therapeutic effect was compared between the three groups according to the Lysholm knee score by variance analysis test,group A compared with group B, P > 0.05, the difference was not statistically significant,group A and group C compared, P < 0.05, the difference was statistically significant, group B compared with group C, P < 0.05, the difference was statistically significant; and according to the HSS score system, between the three groups comparison, P<0.05, the difference was statistically significant;(7) Total curative effect comparison of the three groups after 1 weeks and 1 month after all treatment,by analysis of variance test, P < 0.05,the difference has statistical significance, it can be considered that there are differences between the three groups, the overall efficacy of C group were better than that of group A and group B.Conclusion : Safflower injection of Articular Cavity Flushing with Crochet in the treatment of osteoarthritis of the knee achieved better long-term clinical efficacy,and that is better thAn simple use of joint cavity flushing,itsa safe and effective treatment for KOA. |
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