Font Size: a A A

Differentiation Between Benign And Malignant Focal Ground-Glass Opacity (GGO) On High Resolution CT/Multi-planar Reconstruction (HRCT/MPR)

Posted on:2017-02-08Degree:MasterType:Thesis
Institution:UniversityCandidate:SureshFull Text:PDF
GTID:2334330491464216Subject:Imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Purpose:The purpose of this study was to evaluate the imaging findings of benign and malignant lung focal nodular lesions with high resolution CT (HRCT) and multi planar reconstruction (MPR).Method and Materials:The demographic data of 40 patients presented with pulmonary focal ground glass opacity are pathologically and clinically confirmed, lesion size, lesion location, attenuation value, HRCT/MPR characteristics including shape, interface sign, air bronchogram, pleural indentation, vascular involvement were retrospectively analyzed, which 15 cases of benign lesions,25 cases of malignant lesions. Using chi square test and Fisher’s exact test to analyze the imaging differences of the malignant focal nodular.Results:40 cases of patients including 15 cases of benign and 25 malignant, benign nodules discovered for the first CT signs and malignant nodule in nodule size, lobular location, CT heterogeneity, pleural indentation sign and air bronchogram sign for malignant nodules was statistically significant. The sensitivity of vascular invasion in malignant tumors was 88%, the specificity was 73%, and the accuracy was 78.8%. In the same CT, the sensitivity was 88%, the specificity was 93.3%, and the accuracy was 88.9%. The sensitivity, specificity and accuracy were 92%,93% and 92%, respectively. There were 92% sensitivity,93% specificity, and 92% accuracy in the air. All benign ground glass nodules were observed three months after the review of CT completely disappeared or decreased in volume, while the malignant nodules did not change or increase in volume after three months.Conclusion:Heterogeneous, pleural tag, air bronchogram sign are strongly suggestive of malignancy. Follow up for 3 months, for those that is difficult in diagnosis of the lesion; thereby reducing excessive surgical treatment.
Keywords/Search Tags:GGO, HRCT, sensitivity, specificity
PDF Full Text Request
Related items