Clinical Observation Of Infant Eczema Who Has Food Intolerance By The Way Of Additive ShenLingBaiZhu Powder And Dietary Intervention

Objective: To observe the infant eczema who has food intolerance by the way of additive ShenLingBaiZhu Powder and dietary intervention, and the change of food-specific IgG of pretherapy and post-treatment, to apply the foundation for the spleen invigorating theory treating food intolerance and other relevant disease.Methods: Choose met the inclusion criteria of 69 cases of infant eczema, according to a coin toss prior to treatment were randomly divided into treatment group(36 cases) and control group(33 cases). All children with severe lesions given corticosteroids, antihistamines, anti-infective medication, control group in accordance with food intolerance test results, the treatment group given medicine ShenLingBaiZhu Powder on the basis of dietary intervention. 3 months for a course of treatment. The first two weeks, one month after treatment to the hospital referral or follow-up, 3 months to the hospital review and check food intolerance. Observing two groups’ effectiveness, changes in food-specific IgG and statistical analysis, following-up children after 1 month treatment.Results:1.14 kinds of food intolerance test results, eggs highest positive rate, 84.1%, mostly +2, + 3; milk, followed by 82.6% to +2, + 3 as the main stage; other food-positive from high to low were wheat, soybeans, tomatoes, rice, cod, shrimp, corn, crab, beef, mushrooms, chicken, pork.2. 69 cases of infant eczema, the majority of children with food intolerance in two kinds or more. Food intolerance is one kind of 14 cases, the total number of 20.29%; for the two kinds of food intolerance in 16 cases, the total number of 23.19%; food intolerance into three or more in 39 cases, the total number of 56.52%.3. Comparison of the effects of eczema: After 2 weeks treatment, the cure rate 5.56%, efficiency 30.56%; control group was 3.03%, efficiency 24.24%, rank sum test, Z =-1.002, P = 0.316( P> 0.05), the difference was not statistically significant.After one month of treatment, the cure rate was 19.44%, efficiency 69.44%; control group was 9.09%, the efficiency of 42.42%, rank sum test, Z =-2.500, P = 0.012(P <0.05) The difference has statistically significant.After 3 months of treatment, the cure rate was 69.44%, efficiency 97.22%; control group, the cure rate was 39.39%, 78.79% efficiency, rank sum test, Z =-2.790, P = 0.005(P <0.01) the two groups have significant difference.4. Food intolerance improvement: compare the level of food intolerance cases before and after treatment, by rank sum test, Z =-0.019, P = 0.000(P <0.01), there have significant differences, indicating ShenLingBaiZhu Powder and dietary intervention can improve food intolerance.Ratings cases in the control group before and after treatment of food intolerance, rank sum test, Z =-2.970, P = 0.003(P <0.01), there are significant differences, indicating that a simple dietary intervention may also improve food intolerance.Food intolerance level cases after treatment group and the control group, rank sum test, Z =-3.057, P = 0.002(P <0.01), there was a significant difference between the two groups, the treatment group than the control group.5. Compare the cure rate of relapse in children: treatment group, 25 cases were cured, 1 case of recurrence(4%); control group cured 13 cases, 1 case of recurrence(7%), the Fisher’s exact test, P = 1.000,(P> 0.05), indicating that the two groups showed no significant difference in recurrence.Conclusion :1. The region suffers from eczema infant food intolerance to eggs, milk-based, and in more severe intolerance to.2. The infants and young children suffering from eczema food intolerance are mostly two kinds or more, only one kind of food intolerance is 20.29%; two kinds of 23.19%; three kinds and more than 56.52%.3. ShenLingBaiZhu Powder dietary intervention and food intolerance in infants eczema associated with better clinical efficacy, can reduce the level of food intolerance, and better than dietary intervention, can reduce infant eczema the recurrence rate. From spleen invigorating theory treating food intolerance and related infant eczema, it has the double benefit of power.4. ShenLingBaiZhu Powder and dietary intervention related to food intolerance in infants eczema is good safety.