Evaluation Of Risk Factor For New Onset AF After Off Pump CABG

Background: Post operative Af is very common compliacation encountered in about 30 to 40% patients after cardiac surgery.It result in increase mortality morbidity prolong ICU and hospital stay,incease risk of embolilc stroke and increase expanses of treatment.Objective:The aim of this study was to evaluate the current state of knowledge of risk factor,and mechanisim of development and treatment and prevention of post on pump CABG atrial fibrillationMethod:From Jan 2014 to Dece..2015 158 patient underwent elective coronary artery bypass graft surgery were analyze retrospectively,of these patient 3 patient had preoperaive af so they were excluded from the study,all of the surgery were perform off pump except for 5 who went on pump CABG out of othese five 3 patient who were hemodynamically unstable and need intraoperative conversion to on pump CABG and 2 underwent elective on pump CABG.The patient of this study were divided into two group on the basis of wether they develop Af or not;Group A were those patient who develop Af,Group B were those patient who didn,t develop AF.The association of different risk factor with the occurence of post CABG AF were tested by,t test,calibration chi-square test,Fisher probability method for accurate single factor analysis;Single factor analysis P < 0.1 project index into multiple factors Logistic regression analysis,the multivariality logistic regression is statistically significant:P < 0.05.Result:Results: 1)155 patients,new-onset postoperative atrial fibrillation in 33 cases,the rate was 22.45%;2)18 alternative risk factors by univariate analysis of variance,in which age,diabetes,left ventricular function(class II-IV),thyroid dysfunction,chronic lung disease,postoperative mechanical ventilation,postoperative serum potassium concentration,the concentration of postoperative serum magnesium,β-blockers,cardiopulmonary bypass,left atrial diameter,total P values of 11 alternative risk factors is less than 0.1,any risk factor whos impact on postoperative atrial fibrillation is more significant;enter multi-factor Logistic regression analysis;3)age,postoperative serum concentration of potassium,β receptor blocker in the multivariate analysis lag agent,cardiopulmonary bypass,left atrial diameter increase P value less than 0.05,coronary artery bypass graft surgery is an independent risk factor for new-onset atrial fibrillation,the OR are 2.03,1.04,1.02,0.91,2.39.Conclusion:Pathophysiological mechinism of the development of new onset is not completely understood.In the study we conducted the rate of AF devlopment is 22.45% and also concluded that increasing age and LA diameter is independent risk factor for the development of Post operative AF.Which is supported by many article in the letrature...