Purpose : To summarize the correlations between various TCM syndromes of breast hyperplasia and color Doppler flow imaging, and research the differences in the color Doppler flow imaging signs of different different TCM syndromes, for striving to provide an objective imaging basis for the TCM syndromes of breast hyperplasia.Method : Divided 194 patients with breast hyperplasia into three syndrome groups——liver qi stagnation, incoordination between the Chong and Ren Meridians and obstruction of phlegm and stasis——in accordance with the diagnostic criteria,observed the ultrasonographic and hemodynamic features of breast hyperplasia using color Doppler ultrasound, analyzed the correlations between the TCM syndromes of breast hyperplasia and color Doppler ultrasonography findings, and compared the difference in color Doppler ultrasonogram and haemodynamics between the patients with different syndromes.Result:1. Among liver qi stagnation, incoordination between the Chong and Ren Meridians and obstruction of phlegm and stasis, liver qi stagnation accounts for 52.58%,obviously higher than obstruction of phlegm and stasis and incoordination between the Chong and Ren Meridians.2. Patients’ age, disease duration, pregnancy frequency, induced abortion times and clinical history have impacts on the distribution of TCM syndromes. The duration of liver qi stagnation is relatively short. The duration of obstruction of phlegm and stasis is relatively long. Many of the patients have both breast intracanalicular fibroma and hysteromyoma, while many others suffer from both incoordination between the Chong and Ren Meridians and breast intracanalicular fibroma. Those with incoordination between the Chong and Ren Meridians are relatively older, got pregnant for relatively more times and underwent relatively more induced abortion, so many of them undergo a decrease in progesterone level and undergo an increase in luteinizing hormone level at luteal phases.3. The ultrasonogram of liver qi stagnation is graded lower than that of obstruction of phlegm and stasis and incoordination between the Chong and Ren Meridians. The ultrasonography of simple hyperplasia happens mostly in liver qi stagnation, while the ultrasonography of cystic hyperplasia happens mostly in obstruction of phlegm and stasis, and there is no statistically significant difference in the ultrasonography of solid masses between these two syndromes;4. No blood flow signal is detected in 118(60.82%) of the 194 patients, while blood flow signals are detected in 76 cases(39.18%), but most of the signals are level-I and level-II II ones, while few are Level-III ones;5. Blood flow signals are graded during obstruction of phlegm and stasis, flow velocity is maximized at constriction phase, flow velocity is minimized at relaxation phase, and vascular resistance index is high. This is consistent with the conclusion“there are rich flow signals when solid mass-type breast hyperplasia attacks”.Conclusion : The patients with different syndromes of breast hyperplasia have different color Doppler flow imaging manifestations. Ultrasonography can be used as a reference standard of diagnosis for the TCM syndromes of breast hyperplasia due to its great significance to the improvement of TCM syndrome diagnosis accuracy. It deserves further investigation. |