Synergetic Effect About Mositenning Dryness Formula Of Lu Combined With Acupuncture In The Treatment Of Dry Eye Symptom Of Primary Sjogren’s Syhdrome

Primary Sjogren’s syndrome(PSS)is an autoimmune disease withclinical violations salivary, lacrimal gland, also accompanied the detriment of other exocrine glands. Dry mouth, dry eyes are the main typical clinical manifestations, in addition to recurrent parotid swelling, joint pain, dental caries, purpura, more urine is characteristic of its clinical manifestations. If PSS continues to progress, it can cause patients with multi-organ, multi-system damage, such as interstitial lung fibrosis, atrophic gastritis,chronic pancreatic damage, kidney failure and other complications. The modern medical researches on PSS currently are atthe initial stage, its etiology and pathogenesis is not very clear. Therefore for the treatment of clinical disease we lack of effectiveness of targeted therapeutic drugs and measures. Drugs commonly used in clinical practice are systemic corticosteroids, immunosuppressants and other drugs for local symptoms such as dry mouth, dry eyes. These do have a certain role in mitigation, but poor long-term efficacy and long-term effects on the body side effects, the treatment effect is not ideal. Therefore,, there is significant clinical advantages, significant symptom relief,safety, less side effects for the use of Chinese medicine combined with acupuncture to treat the diseaseProfessor Lu Zhizheng, medical master, is a engaged in clinical research, of traditional Chinese medicine for 70 years, cofined "dry Bi" to Primary Sjogren’s syndrome. He created an basic law, "tonifying qi and nourishing yin" and "lushirunzao presicription" to treat the disease.1 ObjectiveTo evaluate "lushirunzao presicription" combined with acupuncture therapy Yin Deficiency type of primary Sjogren’s syndrome symptoms of dry mouth efficiency of clinical efficacy and clinical value.2 MethodsThe clinical trials are based on the "capital project the characteristics of clinical application " Project Topic: "Study of Primary Sjogren’s Syndrome road’s efficiency moistening soup combined with acupuncture therapy", a total income of 62 cases comply with dry Bi Qi and Yin deficencytype of primary Sjogren’s syndrome, a randomized, controlled, single-blind(blinded evaluator) research methods, clinical taking medicine combined with acupuncture therapy group(acupuncture twice a weekthe following points: Sanyinjiao, the full three years, Kung-sun, according to the sea, in the abdominal, Hegu, the customs, foreign relations, Lian Quan and other points) and taking the medicine packets, namely the treatment and control groups. Observation of treatment is four months of follow-up were evaluated at each time point, set the evaluation time point, namely both before treatment and after the trial began1,2,3,4,6,8,10,12,14,16 week, TCM symptoms of dry mouth, dry mouth VAS(visual analogue scale) scores, traditional Chinese medicine syndrome, joint pain and other symptoms of nocturia were observed and compared, and clinical laboratory tests,namely in the treatment 0,3 month, while non-oral examination, including the stimulation of salivary flow rate test, urine routine, liver and kidney function,rheumatoid factor RF, ESR, immunoglobulin electrophoresis, ANA antibody repertoire,follow-up treatment of the data obtained from each node and before and after treatment laboratory data for statistical analysis in order to evaluate the clinical efficacy of the "lushirunzao presicription" combined with acupuncture therapy yin Deficiency type of PSS symptoms of dry mouth.3 Resultsacupuncture for improving the efficiency of dry mouth symptoms of Sjogren’s syndrome is not statistically significant difference, but the trend improved in both groups, the total effective rate 84.1%. VAS scores of symptoms of dry mouth treatment group compared with the control group were statistically significant differences(P<0.01), compared with safety indicators before treatment had no statistically significant difference(P> 0.05)4 ConclusionAcupuncture for the treatment of subjects with primary Sjogren’s syndrome and xerostomia decreased serum immunologic parameters synergistic treatment, though not a statistically significant difference, but for Sjogren’s syndrome treatment trends and improve posture. Further research intended to prolong the course of treatment and to increase frequency of treatment thorns and to expand the sample size.