Dynamic Analysis In The Perfusion Process Of The Hepatic Vessels

Liver transplantation is the only effective method for the treatment of end-stage liver disease. The quality and level of liver donor liver transplantation is one of the key links to the success rate of liver transplantation. However, in recent years, the source of liver donor is in short supply, and the standard of liver transplantation is weakened. The mechanical analysis of blood vessels and the corresponding mechanical analysis will be helpful to reduce the influence of subjective factors on the quality of cleaning, and it provide theoretical basis for the operation.Objective The hydrodynamic behavior of the perfusion process(cleaning) of the liver endovascular before the operation was studied. On the basis of the data of medical images, the straight vessels and blend vessels models are constructed.A mathematics method has been put forward to estimate perfusion speed and simulation software is used to simulate the flow of intravascular perfusion liquid. Methods With the physical parameters of a medical infusion liquid measured, an estimation method of perfusion parameters was proposed. A straight and a curved First-Class vascular entity model with foreign matter and the control equations of turbulence liquid in vessel were established. The simulation was performed by changing technical parameters of the perfusion. Under the condition of liquid-solid coupling, the mechanics characteristic analysis of the vascular wall and the optimization of perfusion parameters have been put forward. Results Based on the control equations of turbulence liquid in vessel and the preliminary calculated results using the vessel model, the results correspond with the value of the real operation. The simulation results showed clearly the fluid dynamics behavior around the foreign matter, the velocity of the fluid and the wall pressure of the vessel. At the same time, the optimal values of the parameters of the blood vessel perfusion were obtained under the condition of fluid-solid-heat coupling field. Conclusions With the increasing velocity of the entrance perfusion, the pressure and the velocity field are increased in the two types of the vessel model. The negative wall pressure and recirculation region appeared and located in the foreign matter. Because of the influence of the shape, the fluid dynamics behavior in the curved vessel model is more complicated than that in the straight vessel model. Methods proposed in this paperare feasiblein estimating perfusion velocity by which the simulation results show that ofall factors for vessel wall characteristics in the process of perfusion.The influence degree from high to low is shown following: blockage degree, shape of blood vessel andthe location of foreign bodies.