| This study was conducted to investigate the application of a novel bacillus subtilis in weaned piglets. Production performance, blood biochemical parameters, apparent digestibility, diarrhea index, rectal microflora, serum antioxidant index and hormone levels were measured.96 21-d piglets were divided into two treatments; piglets in the control group were fed of the basal diet, while piglets in the test group were fed of diet supplemented with 100 g/t bacillus subtilis. Results showed that:(1) The bacillus subtilis improved feed intake and average daily weight gain, reduced feed conversion ratio, In 15-28 days and 29-35 days after weaning, average daily weight gain was significantly increased by 21.86% and 18.31, while feed conversion ratio was significantly lowered by 9.36% and 11.65%. Total protein and globulin were significantly increased by 5.51%(P<0.05), while blood urea nitrogen levels were significantly reduced by 17.14%(P<0.05), and the serum ALB was not significant affected (P>0.05). (2) Apparent digestibility was improved in some degree, and ether extract were significantly increased by 15.70% and 30.09% at 14 and 28 day after weaning, dry matter was increased by 7.64% at 14 day after weaning; diarrhea rate were reduced by 7.79% in 1-14 days after weaning (P<0.05) with bacillus subtilis supplementation; colonies of rectum lactic acid was significantly increased by 32.08%(P<0.05); colonies of E.coli was significantly decreased 29.38%(P<0.05). (3) Bacillus subtilis improved antioxidant capacity of weaning piglets, MDA was reduced by 29.37%(P<0.05), SOD was increased by 26.33%(P<0.05), T-AOC was increased by 42.86%(P<0.05); serum thyroxine was increased (P>0.05) with bacillus subtilis, T3 and T4 was increased by 17.32% and 14.33%, respectively. |
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