The Study Of Hydrolysis Products Of NMP And Influencing Factors On NMP Hydrolysis

N-methyl pyrrolidone(NMP)is a chemical product and it's a heterocyclic organic compoundmaterials.It is widely used in material synthesis,petrochemical,bio-pharmaceutical and so on,due to the advantages in strong polarity,low viscosity,strong dissolution,low toxicity,and biodegradability.As a result,the hydrolysis of the recovery and recovery process has become a research hot spot.The main purposes of the present study was the hydrolyzate and hydrolysis mechanism under alkaline conditions,and the effects of temperature,alkali and water on the hydrolysis of NMP.The hydrolyzate of NMP was mainly N-methyl-4-aminobutyric acid analyzed by Fourier transform infrared spectroscopy(FTIR),gel permeation chromatography(GPC),mass spectrometry(MS)and nuclear magnetic resonance(1HNMR).5-Hydroxy-N-methyl pyrrolidone(5-HNMP)and N-methylol pyrrolidone(NHMP)were generated in small amounts and both were ring-opened to form N-methyl-4-hydroxyaminobutyric acid and N-hydroxymethyl-4-aminobutyric acid.The possible mechanism of hydrolysis of NMP was discussed.In the alkaline environment or at high temperature,three C-N adjacent to N could be activated.When the C of C=O was activated,NMP ring-opening hydrolysis would happen and then form N-methyl-4-aminobutyric.When the C of methylene and methyl adjacent to N was activated,firstly,the oxidation reaction would occur to form peroxide,which was easy to generate hydroxyl due to instability,while the 5-HNMP and NHMP were formed.Even at the alkaline environment,5-HNMP and NHMP were likely to cause ring-opening hydrolysis to form N-methyl-4-hydroxyaminobutyric acid and N-hydroxymethyl-4-aminobutyric acid.Finally,the three hydrolyzates of NMP could be polymerized to produce amide or ester polymers.The conclusions drew by study the effects of temperature,the usage of alkali and water on the hydrolysis of NMP,shows that the higher temperature,the stronger basicity,the more likely to cause hydrolysis of NMP.The inhibition of hydrolysis of NMP appears because of the hydrogen bonds formation between NMP and water at room temperature,while the inhibition disappears due to the destruction of hydrogen bond in the high temperature or strong alkaline environment.Thus the increase of water can aggravate the hydrolysis of NMP.