Study On Multicomponent Reaction Of Carbon Dioxide And Carbon Disulfide Catalyzed By Transition Metal

Carbon dioxide is the main greenhouse gas and abundant,cheap,easily available,and renewable C1 source which is non-toxic,non-flammable,stable and has many other advantages.It is important to develop a new type of atomic economy with carbon dioxide as the basic raw material to convert carbon dioxide into a variety of useful organic chemicals.This paper focuses on the activation and transformation of carbon dioxide.We have achieved the following results in developing multicomponent reactions involving carbon dioxide catelyzed by transition metals :(1)We reported a silver-promoted three-component reaction of o-alkynylanilines,diaryliodonium salts and carbon dioxide.The mild reaction conditions allow efficient access to a borad substrate scope with a wide range of functional groups.(2)We described a Cu(OAc)2-catalyed four-components reaction of olefins,amines,Togni`s reagent II and carbon dioxide to carbamates with high selectivity in good to excellent yield.The reaction has a wide range of functional groups.Various olefins,such as(hetero)aryl ethylene,and aliphatic olefins can be converted the corresponding products.The olefins containing the backbone of the natural product can be converted to the corresponding products in high yields too.(3)We achieved a Cu(OAc)2-catalyed multi-component reactions of alkynes,amines,Togni`s reagent II and carbon dioxide.The bifunctionalization of alkynes is carried out in one step and two different carbamates are obtained under different conditions.When the ligand is added,the trifluoromethylated product is predominant.When the ligand is free,the product containing the amide group is predominant.(4)We reported a Cu(OAc)2-promoted three-component reaction of boronic acid,amines,and carbon disulfide.The reaction takes cheap boric acid as a raw material..The reaction provides a new approach to a wide range of functionalized dithiocarbamates in good to excellent yields.