Epidemiological Study Of Upper Gastrointestinal Submucosal Tumors

Objective To analyze the location, endoscopic features, pathological diagnosis and treatment of the submucosal tumor(SMT) in upper gastrointestinal tract to improve the level of the recognition and diagnosis and treatment on upper gastrointestinal tract SMT.Methods The age, gender, lesion location, size, pathological diagnosis results, endoscopic manifestation features and treatment mode in 189 samples for employing the upper gastrointestinal tract submucosal tumor and histopathological examinations collected in the pathological department of our hospital from September 2013 to July 2015 were performed the statistics.Results Among 189 cases, 68 lesions were in the esophagus, 46 lesions were in the gastric fundus, 47 lesions were in the gastric body, 24 lesions were in the gastric sinus, and 4 lesions were in the duodenum.There were significant differences in the constituent ratio of pathological diagnosis and age in different locations of SMT(P<0.05), there was no significant differences in the gender of SMT patients in different locations(P>0.05).The diameter of the SMT in the esophagus was smallerthan in other parts, the difference was statistically significant(P< 0.05).The gastrointestinal stromal tumor(GIST) was the most common SMT[60.3%(114/189)] in upper gastrointestinal tract, and the stromal tumor size,patient’s age in different locations was different with statistical difference(P< 0.05), there was no significant difference in the gender(P> 0.05). The risk degrees of GIST were divided into 4 degrees, the risk stratification was positively correlated with the tumor size(P < 0.01), and had no significant relationship with gender and age(P > 0.05).Conclusion The constituent ratio of pathological diagnosis and age,and the diameter of SMT in different locations are different, in which GISTs were the most common pathological lesions in upper gastrointestinal tract, its risk degree is positively correlated with the tumor size, which can provide reference for clinical diagnosis and treatment.