| Eyes are one of the most important sensory organs, which allow the human to perceive and obtain the correct information in complex environments. The eye diseases on earth, such as cataracts, glaucoma, seriously affect the quality of people’s life, and damage to eyes under space microgravity not only brings serious harm to the astronaut’s body, but also poses a serious threat to the completion of tasks in space.Existing studies of glaucoma based on hypotheses reasoning and animal experiments, but there is a lack of necessary theoretical support; the subjects in the experiments are not representative, etc. Research progress in eye damage under space microgravity has been slow, due to the high costs of experiments and scarcity of subjects less subjects. This thesis uses the method of finite element analysis through eyeball modeling to analyze biomechanical characteristics of glaucoma and ocular under microgravity environments; to provide theoretical reference for the study of glaucoma and microgravity eye injury under microgravity. The concrete research content is as follows: Analysis of biomechanics of glaucoma and ocular under micro-gravity environment characteristics, and exploring the effects of intraocular pressure exerted by glaucoma and the effects of intracranial pressure under microgravity on the eye tissue biomechanics.A simplified eyeball finite element model, the three-dimensional symmetric ideal eye model and the three-dimensional complex eyeball model are established, and eyeball model constraint methods are put forward by analysis of eyeball anatomy, simplifying the structure of the eyeball. This thesis tries to verify the feasibility of eyeball model constraints through simulation analysis results of simplified eyeball model and comparison with eyeball stress equations based on theoretical values.Through analysis of the pathological characteristics of glaucoma, determine the boundary conditions of the glaucoma model and through the three-dimensional symmetric ideal eyeball model and three-dimensional model of the eyeball simulations of glaucoma analyze stress and strain of eyeball and ocular tissue of glaucoma patients.Through analysis of characteristics of physiological signs under a microgravity environment, determine the boundary conditions of the eyeball model under microgravity and through the three-dimensional symmetric ideal eyeball model and three-dimensional model of the eyeball and eyeball simulation under the microgravity analyze stress and strain of eyeballs and ocular tissue of glaucoma patients under microgravity.Using three-dimensional symmetric ideal eye model to analyze the effects of intraocular pressure or intracranial pressure on the eyeball tissue and to study how eye cornea, optic nerve head and the optic nerve are changing in stress and shape with the change of intraocular pressure or intracranial pressure. |