The Research Of Cancer Burden In China From 2005 To 2009

Objective: To investigate the incidence, mortality and disease burden of China cancer from 2005 to 2009, so as to provide reference for cancer prevention and control. Methods: The cancer registry data of 2008-2012 was collected based on the published CHINESE CANCER REGISTRY ANNUAL REPORT by National Center for Cancer Registries. Population data was from China Population and Employment Statistics Yearbook in 2005 to 2009. The incidence, mortality, Potential Years of Life Lost(PYLL) and Disability Adjusted Life Year(DALY) was used to access the burden of cancer. Relative Ratio(RR) were calculated to assess burden of old people cancer in old people. The comparison of PYLL and DALY in years and gender was used Wilcoxon rank sum test. Results:1. The crude incidence of cancer was 278.66 per 100,000, in which the male and female were 296.23 per 100,000 and 260.60 per 100,000 respectively. The incidence of urban district and rural district was 294.43 per 100,000 and 248.33 per 100,000. The incidence of lung, breast, stomach, cervical, liver was 41.61 per 100,000、35.14 per 100,000、32.58 per 100,000、24.71 per 100,000、20.42 per 100,000 respectively. The incidence of cancer at under 30 age group was low and reach the peak(1586.88 per 100,000) at 80 age group. The incidence of elderly was 8.19 times higher than young people.2. The crude mortality of cancer was 177.58 per 100,000, in which the male and female were 219.23 per 100,000 and 134.78 per 100,000 respectively. The mortality of urban district and rural district was 178.29 per 100,000 and 184.63 per 100,000. The mortality of lung, breast, stomach, cervical, liver was 36.72 per 10,000、33.68 per 10,000、22.31 per 10,000、13.32 per 10,000、6.11 per 10,000 respectively. The mortality of cancer at under 35 age group was low and reach the peak(1533.05 per 100,000) at 80 age group. The mortality of elderly was 13.70 times higher than young people.3. PYLL of cancer were 79427871 person-years(43624678 in male and 35803195 in female) in China from 2005-2009. The PYLL rate(Potential Years of Life Lost rate)of top five cancer was Gastric(3.50), liver cancer(3.15), lung cancer(2.87), esophageal cancer(1.11), breast cancer(0.73). The PYLL rate was lower under 20 age group and increased gradually at 25 age group and reached peak at 55 agegroup. The PYLL rate of elderly was 2.34 times than that of young people.4. The DALY of cancer in China was 92188763 healthy life years(54788569 in male and 37400194 in female) including 90365344 healthy life years due to YLL and 1823419 healthy life years due to YLD. The top five DALY rate of cancer were stomach(3.65), lung(3.56), liver(2.88), esophagus(1.32), rectum(0.63) respectively. The DALY rate of elderly was 4.54 times than that of young people.5. The incidence, mortality, PYLL rate, DALY rate was low at 25 age group and increased gradually after 30 age group, in which reached the highest at 80 age group. The incidence, mortality, PYLL rate, DALY rate of lung cancer, stomach cancer, liver cancer was highest at 80 age group. Top ten cancers, the elderly incidence of prostate cancer, bladder cancer, pancreatic cancer, lung cancer was 4 times than that of young people. The elderly mortality of prostate cancer, stomach cancer, bladder cancer, lung cancer, pancreatic cancer, esophageal cancer, colorectal cancer was 4 times than that of young people. The elderly PYLL rate of stomach cancer, prostate cancer, esophageal cancer, pancreatic cancer, lung cancer was 4 times than that of young people. The elderly DALY rate of prostate cancer and stomach cancer was 4 times than that of young people. The incidence, mortality, PYLL rate, DALY rate of prostate cancer and stomach cancer in elderly was 23.99、30.62、11.32、9.72 and 3.50、8.04、17.9、4.59 than that of young people. Conclusion: The disease burden of cancer in China was serious in 2005 to 2009. The cancer burden of male, elderly was higher than that of female and young people. With the growing aging population and environmental pollution, the burden of malignant disease will worsen. Gastric, lung, liver was the top three kinds of cancer disease burden. Tertiary prevention should actively adopt measures to enhance cancer screening and early detection and treatment, vigorously carry out basic clinical research, effective control of the risk factors and reduce the burden of disease.