Heat Purging Fire On The Stomach Dampness Type Acute Non-variceal Upper Gastrointestinal Bleeding Clinical Observation

Background and purposeAcute non-variceal upper gastrointestinal bleeding is variceal bleeding disorders than non-flexor ligament digestive tract caused by a common clinical acute critical illness, the annual incidence rate of 50-150/100,000, the mortality rate was 6% to 10%. With the rapid development of modern medicine and the continuous improvement of living standards of the national economy, a large number of new drugs and hemostatic endoscopic hemostasis new technology could be widely used in clinical, upper gastrointestinal hemorrhage and achieved satisfactory results, mortality has decreased trend. We must see the upper gastrointestinal bleeding and achieved satisfactory results, should also see the presence of conventional Western medicine treatment markedly slow time, then high risk of bleeding, some drug costs less than the expensive side, but although good endoscopic hemostasis but the equipment is expensive and complicated to operate, the impact of operator skill level, and many other factors, and is not suitable for use in remote areas and the popularity of small hospitals, resulting in relatively backward in terms of basic hospital acute non-variceal upper gastrointestinal bleeding treatment level, when the masses go to hospital, not timely and effective treatment, it is the primary hospital urgent need to find a safe, effective and relatively inexpensive treatment programs to make up for their lack of infrastructure and lack of expensive drugs. The research by observing the heat purging fire Combined with Western parties before and after treatment of stomach dampness type non-variceal upper gastrointestinal bleeding symptoms, signs, rebleeding rate, length of stay changes, clinical efficacy, and with western medicine alone as a control to compare the two advantages and disadvantages, and through fecal occult blood, blood and otner laboratory tests, the difference of the two groups of patients the treatment objective reaction to stomach dampness type non-variceal upper gastrointestinal bleeding in low-risk patients to find a effective and safe, inexpensive therapeutic approach, but also to explore opportunities to provide Chinese medicine in the emergency aspects of clinical applications.MethodsGastrointestinal bleeding in 50 cases of acute non-variceal collect met the inclusion criteria, single-blind randomized controlled trial research, the eligible subjects by 1:1 assigned to treatment and control groups ratio randomization method. Where in the treatment group are 25 patients and in the control group are 25 patients. Control group support therapy plus proton pump inhibitors inhibit gastric acid, hemostatic agents to stop bleeding, treatment options are:sodium chloride injection 20ml plus esomeprazole 40mg intravenously every 12 hours,2 times a day; sodium chloride injection 10ml plus injection hemocoagulase 2u intravenously once a day, treatment for one week. In the treatment group were treated based on the use of heat purging fire side, decoction 100ml, one day, sooner or later take, each 50ml. By hemoglobin before and after treatment, bleeding time, TCM symptom score, fecal occult blood negative time, relatively efficient, and thus heat purging Fire on stomach dampness type non-variceal upper gastrointestinal bleeding in clinical application to evaluate efficacy.ResultsDue to their poor compliance of patients, so that data collection is not complete, it will be poor compliance of patients and control patients (treatment group and the control group 3) removed, the observational data into the computer, the use of statistical software SPSS22.0, statistical analysis, the treatment group, the total efficiency of 95.5% (cure plus markedly plus effective)) the control group, the total efficiency of 91% (cure plus markedly plus effective), indicating that the treatment group than the control group (P= 0.044<0.05), the treatment group in the treatment of stomach dampness type non-variceal upper gastrointestinal bleeding in patients with low-risk aspects of advantages exist.ConclusionCombined heat and purging Fire on western medicine group used to treat stomach dampness type non-variceal upper gastrointestinal bleeding, in an efficient, improve the clinical symptoms and so have better efficacy than the simple comparison group, and has a shorter treatment cycles, cost low, safe and reliable, has great significance for research and clinical applications continue to explore the observation of acute non-variceal upper gastrointestinal bleeding, but also for Chinese medicine in the treatment of upper gastrointestinal bleeding and provide new direction for other accident and emergency treatment.