The Application Research Of 640 One-stop Whole Brain CT Perfusion Imaging Technology In Super Early Ischemic Encephalopathy

Objective To investigate the clinical application value of hyper-acute cerebral infarction using the one-stop whole brain 640-layer computed tomography perfusion imaging technique.Materials and methods:Collecting 25 patients who were cerebral artery blood supply deficiency in the half-year. All patients acceptone-stop whole brain 640-layer perfusion imaging technique.All patients’check time window were within 6 hours.Drawing ROIof Ischemic area in the perfusion pseudocolor images manual.Measurement parametersinclude area of ischemic area and mirror region, cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time to peak (TTP), delay cerebral (DCI). Select the largest ischemic area of the patientsand get the perfusion value of ischemic area and mirror region.The paired t test was used to analyze the experimental data.Result:1. There are 16 patients who were found ischemic area, seven people were found ischemic area in the unilateral hemispheric and mean area of largest ischemic regional was 38.3±3.04cm2;four people werefound ischemic area in the unilateral cerebellar hemisphere and mean area of largestischemic regional was 9.32±3.9cm2;one patient was found ischemic area in the unilateral parietal and the maximum ischemic area was 14.5cm2; one patient was found ischemic area in the unilateral temporal lobe and the maximum ischemic area was 28.9cm2; one patient was found ischemic area in the unilateral occipital ischemia and the maximum ischemic area was 5.4cm2; one patient was found ischemic area in theunilateral corona radiata and the maximum ischemic area was 9.9cm2;one patient was found ischemic area in the unilateral basal ganglia and the maximum ischemic area was 2.8cm2.2.TTP of the largest ischemia area in 16 patients were increased and its value was 18.90±5.77s, it is statistically significant (t=3.720, P<0.01) when compared with mirror region. Compared with the mirror region,the DCI and CBF were obvious differences and their values were 31.65±10.59mL/(100g * min) and 6.91±4.09s, and they are also statistically significant (t=3.720, P<0.01), (t=3.520, P<0.01)compared with the mirror region.3. We should comprehensive consider the site of ischemia,size and value of the perfusion of ischemic areas before thrombolysis therapy. This study suggests we should consider the risks ofthrombolysiswhen the ischemic area is larger than 30cm2 and CBV of this ischemic area is less than 2 mL/100 g.Conclusion:Early ischemic cerebral infarction area can be found with 640 one-step entire cerebral perfusion technique.This technique can also provide guiding when clinical decide to launch intravascular thrombolysis.