Application Of Academic Thought In Fuqingzhu Nuke In Treating Dysmenorrhea By Dampness-heat Of Liver Channel

ObjectiveBy combining literature research and clinical research, to investigate and explore the morbidity situation, the etiological factors and pathogenesis of dysmenorrhea of dampness-heat of liver channel from south of the Five Ridges.To systematically elaborate the pathogenesis of dysmenorrhea of dampness-heat of liver channel and to proof the exist of this pattern of syndrome of dysmenorrhea. To evaluate the response of treatment of hodifying xuanyutongjing decotion, which may carry forward Professor Lu zhizheng’s academic thought of dampness and provide reference to enrich syndrome differentiation and treatment in gynecology of traditional Chinese medicine.MethodsResearch for modern literature by advanced search in Chinese Journal Full-text Database. The subject words are dysmenorrhea, including liver, dampness-heat or dampness-heat of liver channel. Research the Chinese Medical (Electronic and Audio-visual Press of Hunan. ISBN 7-900377-49-2/R·8) by keyword dampness-heat of liver channel for ancient books. Then formulate a traditional medicine syndrome scoring table. Treat dysmenorrhea by hodifying xuanyutongjing decotion four to seven days before menorrhea. Seven days for one period of treatment. Observe the change of pain degree, symptoms of dysmenorrhea and traditional medicine syndrome. Compare them by method of pre and post. Sort data by Excel and analyze the data by SPSS19.0 statistical software, measurement data using t-test, calculators information using chi-square test, ranked data using rank sum test.Results1. Document ResearchThe number of researching for modern literature is respectively 218(subject word is dysmenorrhea, including liver),33(subject word is dysmenorrhea, including dampness-heat)and 1 (subject word is dysmenorrhea, including dampness-heat of liver channel).231 of them valid(multiple contributions with one manuscript is excluded).9 of them refers to dysmenorrhea of dampness-heat of liver channel. At the same time, we searched out 227 items from the Chinese Medical.34 of them refers to women’s dampness-heat of liver channel. The modern literature researched does not include pain of upper legs medial, rectal pain and itching of vagina or vulva, which have correlation with dampness-heat of liver channel in some ancient books.2. Clinical ResearchIn the curative effect of symptom of dysmenorrhea,4 cases (11.4%) were cured,14 cases (40.0%) were markedly improved,9 cases (25.7%) were effective, invalid 8 cases (22.9%), the total effective rate was 77.1%. In the curative effect of traditional medicine syndrome,3 cases (8.6%) were cured,19 cases (54.3%) were markedly improved,11 cases (31.4%) were effective, invalid 2 cases (5.7%), the total effective rate was 94%. Through comparing the scores before and after treatment by pair T test, differences were statistical significance (p< 0.05).The result explains that xuanyutongjing decotion improves symptoms of dysmenorrhea and traditional medicine syndrome of dampness-heat of liver channel. The effect is obvious.ConclusionAncient and modern documents have put forward dysmenorrhea of dampness-heat of liver channel which is a real existence in clinical practice. But the related studies are not enough to discuss the etiopathogenesis of dysmenorrhea of dampness-heat of liver channel systematically.This TCM type is often ignored or misunderstood in syndrome differentiation, which may influence efficacy of TCM. Exogenous hot and humid, and stagnation of liver qi and spleen deficiency are the two major etiological factors of dysmenorrhea of dampness-heat of liver channel. The main pathogenesis is closely related to dysfunction of liver controlling dispersion which may deliver result of stagnation leading to pain. The syndrome characteristics reflect on the circulation of liver channel.Treating dysmenorrhea of dampness-heat of liver channel by hodified xuanyutongjing decotion can not only improve symptoms of dysmenorrhea and traditional medicine syndrome, but also reduce the degree of pain and improve the concomitant symptoms. It has achieved a significant curative effect.