| Objective:To explore the clinical efficacy of catheter-directed thrombolysis and systemic thrombolysis for acute lower extremity deep venous thrombosis, and analyze the advantages and disadvantages of the catheter-directed thrombolysis.Method:Retrospective analysis of 167 cases of acute lower extremity deep venous thrombosis in the Department of vascular surgery, Kunming general hospital from February 2016 to January 2014. The 167 patients were divided into group A:system thrombolysis; group B:CDT. The total effective rate, cure rate, and the rate of limb circumference, vein patency rate and complications were compared between the two groups in the near future and 6-12 months.Result:After treatment, two groups of patients with lower limb swelling symptoms were improved to varying degrees. Before and after treatment, the difference of the circumference of thigh and leg, group A was (3.2+0.7), (3.2+0.5), group B was (4.1+0.9), (3.6+0.6), the circumference of thigh and leg of group B was significantly higher than that of group A. Recently, followed up for 6-12 months total efficiency, the cure rate, the vein patency, group B were higher than group A (P< 0.05), during the treatment of bleeding complications in group B was slightly lower than that in group A, patients were followed up for 12 months. The incidence of PTS, B group was significantly lower than that of the group.Conclusion:(1) CDT in the treatment of acute lower limb deep venous thrombosis in the near future and long-term efficacy are better than the system thrombolysis.(2) CDT treatment of acute deep venous thrombosis of lower extremity, is a simple, safe and effective treatment method, has a good clinical application prospects. |