Study On The Relationships Between The Distributions Of Symptoms Of Traditional Chinese Medicine And Relative Factors Of Reflux Esophagitis

Objective:To study on the relationship between the main distribution of Traditional Chinese Medicine (TCM)syndrome types and relative factors in patients with Reflux Esophagitis(RE) in Xiamen area. To learn more about the epidemiological characteristics of RE in this area, it is conducive to guide the clinic dialectical, so as to improve the therapeutic effects.Method:Using the clinical epidemiological method.365 cases with RE who first seeking for medical advice were selected as the research subjects to investigate the TCM syndrome types, specific symptoms, signs and related factors of them in Xiamen area during 2015 Jan to 2016 Jan. All the data were analyzed by statistics.Results:1. In the observation cases, there were 97 cases of incoordination between liver and stomach syndrome,46 cases of spleen-deficiency and Qi stagnation syndrome,74 cases of spleen insufficiency stomach heat syndrome,68 cases of heat syndrome of liver depression. 37 cases of Qi deficiency and blood stasis syndrome.43 cases of syndrome of combination with cold and heat. There was a significant difference (P<0.05) between syndrome types. Syndrome types of incoordination between liver and stomach and dampness-heat due to spleen deficiency were significantly more than other syndromes (P<0.05).2.264 cases were male (72.33%),101 cases were female (27.67%), the sex ratio is about 2.6139:1; there were significant differences in the pathogenesis of this disease in gender (P<0.05). The sex ratio of each syndrome was statistically significan(P<0.05),especially for spleen insufficiency stomach heat syndrome and heat syndrome of liver depression along with syndrome of combination with cold and heat(P<0.01).There was a statistical difference between different ages (P<0.05), with 40-59 years old population distribution at most (243 cases,66.58%).3. The main symptom of each syndrome types were as follows: ①Incoordination between liver and stomach syndrome:acid reflux, hypochondriac pain, heartburn, belching, retrosternal pain;②Spleen-deficiency and Qi stagnation syndrome:lassitude, loose stool, anorexia, stomachache, acid reflux;③Spleen insufficiency stomach heat syndrome:heartburn, stomach noisy, acid reflux, stomachache, gastrectasia;④Heat syndrome of liver depression: dry mouth and bitter mouth, heartburn, acid reflux, belching, hypochondriac pain;⑤Qi deficiency and blood stasis syndrome:lassitude, anorexia, loose stool, throat discomfort, heartburn;⑥Syndrome of combination with cold and heat:cold limbs, acid reflux, throat discomfort, heartburn, dry mouth and bitter mouth.The main symptom of each syndrome had a significant difference (P<0.05).4.186 cases were with helicobacter pylori infection (50.96%),179 cases were without helicobacter pylori infection (49.04%).There was no significant difference in the infection status of helicobacter pylori among the 365 patients with RE (P>0.05).5. In terms of related lifestyle factors, special hobbies of patients with RE include work strain(266 cases), gloomy emotion (265 cases), irregular diet (258 cases), addicted to drinking (257cases), eating sweets (253 cases) etc.Work strain and gloomy mood had the highest rates of syndrome of heat syndrome of liver depression(P<0.05). Irregular diet and addicted to drinking had the highest rates of spleen insufficiency stomach heat syndrome(P<0.05). Eating sweets and eating cold had the highest rates of spleen-deficiency and Qi stagnation syndrome(P<0.05). Overwork occured mostly in Qi deficiency and blood stasis syndrome(P<0.05).6. Patients’ educational attainments had a statistically significant (P<0.05) in the pathogenesis of RE in patients with highly education (including high school, college and higher education) totaled 224 cases (61.37%), higher than patients with middle school education or less (P<0.05). The number of professional and technical personnel were significantly more than other occupational group (P<0.05).Conclusion:1. In patients with reflux esophagitis of Xiamen area, male were more than female.The incidence of this disease focused on middle-aged people. Besides, patients with highly education and mental workers especially professional and technical personnel should pay more attention to the prevention and treatment of RE.2. In this study, we found that incoordination between liver and stomach syndrome was the most common of TCM syndrome types in patients with RE. Spleen insufficiency stomach heat syndrome took the second place, and heat syndrome of liver depression of the third, and spleen-deficiency and Qi stagnation syndrome in the fourth, which was more than syndrome of combination with cold and heat.Qi deficiency and blood stasis syndrome was the least. The main syndrome types of RE were mostly sthenia syndromes.3.The positive rate of the helicobacter pylori was 50.96% in 365 patients with RE. There was no significant difference in the infection status of helicobacter pylori among different syndromes(P>0.05).4. In the treatment of RE, we should pay attention to guide the patients to regulate emotions, attention to diet, fatigue and other factors, in order to better play the role of the non-drug treatment and the prevention this disease in TCM.