The Value Of Ultrasound, Mammography, MRI And Tumor Markers Combined Application For Breast Masses

Objective:To compare the mammography, ultrasound, magnetic resonance imaging and tumor markers in diagnosis of breast masses, evaluate the diagnostic accuracy of the examination methods and diagnostic features, choose the best breast examination.Materials and Methods:A retrospective analysis of January 2015 --August 2015 to Guangxi Medical University First Affiliated Hospital,824 cases of breast tumor cases surgical treatment of gastrointestinal glands to pathological findings diagnostic gold standard to compare ultrasound, X-ray mammography, MR and tumor markers in the diagnosis of breast masses sensitivity, specificity and diagnostic accuracy. Then selected from 824 cases in all do ultrasound, mammography breast cancer patients, MRI and tumor markers, a total of 149 cases, the sensitivity analysis of different combinations of inspection methods.Results:824 cases of breast masses, ultrasound, mammography, MRI sensitivity are:84.2%,68.9%,91.9%; specificity was:71.0%,79.6%,69.9%; diagnosis was:74.1%,74.5%,82.9%. Of five serum markers of AFP, CEA, CA153, CA199, CA125 sensitivity were:3.3%,19%,33.1%,10.8%,16.8% and specificity were:98.7%,99.0%,91.1%,96.8%,95.2%; diagnosis rates were 62.9%,68.9%,69.1%,64.5%,65.7%. AFP has no significant difference in benign and malignant breast lesions.149 cases of all do ultrasound, mammography breast cancer patients, MRI and tumor markers, the sensitivity and the whole group of 824 cases of examination ultrasound, mammography, MRI and tumor markers are substantially the same. Joint inspection and analysis, the sensitivity of ultrasound+mammography was 86.6%, the difference compared with the combination of mammography+ultrasound+ MRI, ultrasound+MRI+mammography+tumor markers showed no significant statistical significance. For patients with clinical stage I, ultrasound, mammography, MRI, CEA, CA153, CA199, CA125 sensitivity are:72.5%, 70.7%,88.0%,6.5%,17.7%,3.2%,11.3%.Conclusion:1, ultrasound, mammography and MRI in the diagnosis of breast disease have a higher diagnostic value for the diagnosis of early breast cancer have a greater significance.2, tumor marker CA15-3, CA125, CEA, CA199 can be used as a reference index diagnosis of breast cancer, but the sensitive is less than ultrasound, mammography and MRI.3, the sensitive of mammography combined with a combination of ultrasound is 86.6%, which is more reasonable joint detection, and low cost, it is recommended as a routine joint inspection methods.4, the sensitivity of MRI is the best breast diagnosis of breast disease, but MRI diagnosis is higher costs, long waiting time.MRI diagnosis of suspicious breast masses is meaningful.For breast masses MRI is not recommended as a routine screening method...