The Study Of The Correlation Of Androgenetic Alopecia And Metabolic Syndrome

Objective1. We detect different ages groups androgenetic alopecia(AGA) patients fasting plasma glucose,TG, TC, HDL-C, LDL-C, Waistline, BMI, blood pressure and indicators associated with metabolic syndrome(MS), to investigate the rela-tionship between AGA and MS.2. We study the correlation between alopecia scale, TCM syndrome and indicators associated with MS such as fasting plasma glucose, TG, TC, HDL-C, LDL-C, Waistline, BMI, blood pressure, which can probably provided new clues for the prevention and treatment of MS in AGA patients.MethodsThere were 168 AGA patients and 170 healthy control in the study group. We observed two groups of fasting plasma glucose, TG, TC, HDL-C, LDL-C, waistline, BMI, blood pressure and indicators associated with MS, and we would make a statistical analysis of the data.Results1.In this study, AGA patients complicated with MS were 12 cases(7.14%), while healthy controls complicated with MS were 4 cases(2.35%).The Probabi-lity of AGA patients with MS was significantly higher than that in healthy controls, and the difference was significant.2. Among the 168 cases of AGA patients 69 cases had family history, accounting for 41.07%.3. Fasting TC and LDL-C level and its abnormal rate of three age groups that AGA patients in Guangdong area at the age of 20 to 25,26 to 30,31 to 35 were significantly higher than those of healthy controls, while the difference was significant.4. Alopecia scale for AGA patients in Guangdong area were clasified accord-ing to Hamilton-Norwood scale grouping criteria. There were 60 people in grade 11(35.71%),57 in grade â…¢(33.93%),51 in grade â…£(30.36%). Age had little or no effect on LDL-C and TC, while alopecia scale was positively correlated with LDL-C and TC. The higher level of alopecia scale, the higher risk of MS.5. TCM syndrome for AGA in Guangdong was mainly the syndrome of deficiency of liver and kidney, accounted for 41.67%. While the syndrome of endoretention of damp heat was 35.71%, and the syndrome of blood deficiency and wind dryness was 22.62%. Different TCM syndrome for AGA patients had different indicators associated with MS. Fasting TC and LDL-C level and abnormal rate in AGA patients with the syndrome of endoretention of damp heat was significantly higher than that of AGA patients with the syndrome of deficiency of liver and kidney and AGA patients with the syndrome of blood deficiency and wind dryness. The syndrome of endoretention of damp heat might be one of the precipitating factors for leading AGA patients to MS. Conclusion1.AGA patients in Guangdong area may be prone to MS. Fasting TC and LDL-C level and abnormal rate in AGA patients was significantly higher than those of healthy control in the same age group in Guangdong area.2. Different alopecia scale for AGA patients had different indicators associated with MS in Guangdong area. Age had little or no effect on LDL-C and TC, while alopecia scale was positively correlated with LDL-C and TC. The higher level of alopecia scale, the higher risk of MS.3. The proportion of AGA patients with different TCM syndromes in Guangdong area from highest to lowest was the syndrome of deficiency of liver and kidn-ey, that of the syndrome of endoretention of damp heat, that of the syndrome of blood deficiency and wind dryness. Different TCM syndrome for AGA patients had different indicators associated with MS. Fasting TC and LDL-C level and its abnormal rate in AGA patients with the syndrome of endoretention of damp heat was significantly higher than that of AGA patients with the syndrome of deficiency of liver and kidney and AGA patients with the syndrome of blood deficiency and wind dryness. The syndrome of endoretention of damp heat might be one of the precipitating factors for leading AGA patients to MS.