| Objective: To study the quality of life for Patients with CHD before and after Percutaneous Coronary Intervention and analyze the Influence Factors of Quality of LifeMethod: CHD patients(n=175) undergone coronary angiography(CAG) and successful implantation of drug-eluting stents(DES) were chosen respectively from Apr. 2013 to Oct. 2014. All patients were given the survey by applying Seattle Angina Questionnaire(SAQ) and clinical general date questionnaire respectively 24 h before and 12 m after PCI. The changes of QOL were compared before PCI and after PCI for 12 m. Depending on the type of patients with coronary heart disease,patients were divided into stability angina(SA) group and acute coronary syndrome(ACS) group, to compare the preoperative and postoperative differences in the quality of life between the two groups of patients; According to coronary angiography in patients with Gensini score, patients were divided into light, medium, and heavy three groups, comparing the difference between the three groups of preoperative and postoperative quality of life. To compare different culture, different income groups preoperative and postoperative differences in the quality of life; With preoperative and postoperative SAQ overall scores as the dependent variable, with age, sex, body mass index, smoking, diabetes, hypertension, coronary heart disease type, number of stent placement, body mass index(BMI), vascular disease variables and Gensini score as independent variables, multifactor stepwise regression analysis for the influence factors in preoperative and postoperative quality of life of coronary heart disease patients;Result : 1. 175 cases of coronary heart disease patients with postoperative SAQ scores was significantly higher than that in preoperative, the postoperative quality of life is improved significantly(p < 0.05), Quality of life improved significantly was different between SA and ACS as well as light and heavy groups(P < 0.05).2. SA compared with ACS in baseline data: between the two groups the Gensini score, the number of vascular lesions, smoking comparison difference was statistically significant(P < 0.05)3.Between the SA and ACS two groups preoperative and postoperative SAQ scores compared:(1) The preoperative quality of life of SA and ACS groups were improved significantly(P < 0.05);(2) In preoperative, two groups in the physical limitation(PL), angina frequency(AF), treatment satisfaction(TS) and total score difference was statistically significant(P < 0.05); in postoperatively, SAQ score difference between the two groups had no statistical significance(P > 0.05).4. Baseline data in three groups: the number of DES difference was statistically significant between light and medium lesion group(p < 0.017), light and heavy lesion group in body mass index, the types of coronary heart disease, smoking and stenting number difference was statistically significant(p < 0.017), medium and heavy lesion group on coronary heart disease(CHD) type difference was statistically significant(p < 0.017), the number of lesion blood vessel was statistically significant difference between three groups(p < 0.017)5.SAQ scores of preoperative and postoperative were compared between three groups :(1)compared with preoperative, postoperative quality of life was significantly improved in three groups(P < 0.05);(2) In preoperative, light and medium lesion group in the treatment satisfaction(TS) difference was statistically significant(p < 0.017);Physical limitation(PL), angina frequency(AF), treatment satisfaction(TS), total scorea were significance different in light and heavy groups(p < 0.017), Physical limitation(PL), angina frequency(AF), total score were significant different in medium and heavy groups(p < 0.017). In Postoperative, there is no significance difference in SAQ score between the three groups(P > 0.05).6. In preoperative and postoperative, patients with different cultural degree and income level on the SAQ total score difference had no statistical significance(p > 0.05).7. Multiple linear regression analysis showed that smoking and the number of lesions vascular were the main factors affecting the preoperative quality of life, smoking and gender were the main factors affecting the quality of life after surgery.Conclusion: 1. PCI can effectively improve quality of life in patients with coronary heart disease, especially the degree of pathological changes serious patients.2. In preoperative, patients with different types and different degree of coronary artery lesions quality of life mainly different in physical limitation(PL), angina frequency(AF), treatment satisfaction(TS);3. IN postoperative,there is no difference in quality of life among patients with different types, different degree of coronary artery lesions;4. The degree of different culture, different income levels interventional therapy in patients with preoperative and postoperative quality of life has no statistically significant difference.5. The influencing factors on the patients, quality of life were smoking number and vascular lesion in preoperative, gender and smoking in postoperative. |
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