Study On Correlation Between TCM Syndromes Of Carotid Artery Atherosclerosis And Mild Cognitive Impairment

Objective : Study of carotid artery atherosclerosis TCM syndrome and the correlation of mild cognitive dysfunction,for the treatment of traditional Chinese medicine dialectical argument carotid atherosclerosis related cognitive dysfunction syndrome differentiation of traditional Chinese medicine therapy provides scientific theoretical guidance.Methods:Has set up the "Shaanxi Province Traditional Chinese medicine and Western medicine combined with prevention and treatment of stroke collaboration",selected to meet the diagnostic criteria of 226 patients, patients to record the information of four diagnostic methods, physical and chemical indicators,neck vascular ultrasound,MOCA cognitive assessment table information,quantitative information as variables,entered into the computer database of SPSS,analyzed the distribution of TCM Syndromes of carotid atherosclerosis,and TCM syndrome type and MCI correlation.Results:Included 226 patients from general situation,analysis of TCM symptoms, syndrome type distribution,mild cognitive dysfunction related factors and carotid atherosclerosis in TCM syndrome type and correlation of mild cognitive dysfunction were analyzed.(1) The distribution of TCM symptoms: the highest frequency of forgetfulness,dizziness,dim complexion,such as clinical symptoms, and stool, turned, spread his hands the symptom such as relatively rare. Pulse condition with string is vein, see more, and generation of pulse, weak pulse,pulse speech &drama,floating pulse is relatively rare.The frequency of the least pulse, slow pulse, pulse condition for late.Tongue distribution in greasy, thick dark purple tongue,tongue coating under tongue ecchymosis petechiae,sublingual veins stood out high frequency;(2)The distribution of TCM syndrome types:in carotid atherosclerosis with mild cognitive dysfunction in patients with TCM syndrome type of the most rare single pass type for the kidney and blood stasis,phlegm and blood stasis mutual junction.And composite syndrome types in kidney and blood stasis+wet indicates sheng,phlegm and blood stasis and phlegm+stasis heat relieving qi deficiency, blood stasis+phlegm wet indicates sheng, kidney and blood stasis, phlegm wet indicates sheng depressi on within+toxic heat, phlegm and blood stasis and relieving solid+hot junction+stasis poison inside depressive frequency is higher; Mild cognitive dysfunction;(3) Related factors analysis: the impact of gender on mild cognitive dysfunction has no obvious difference, and the age and level of education and mild cognitive dysfunction have certain relevance. As the growth of the age, the lower the Mo CA scores.(4)And the selected 226 patients according to the degree of carotid stenosis group, Mo CA score of the patients with two independent samples Ttest, found that compared with moderate stenosis group, mild stenosis exists significant difference(P<0.05),compared with severe stenosis group, mild stenosis group differences statistically significant(P<0.05),while moderate stenosis and severe stenosis group, there was no statistically significant difference(P>0.05).(5)Carotid artery atherosclerosis 10 kinds of TCM syndrome types of order for the influence of the cognitive level of patients with kidney deficiency and blood stasis < alternating knot < phlegm and blood stasis phlegm wet indicates < liver Yang sheng qi deficiency blood stasis syndrone < wind phlegm < Yin pneumatic < toxic heat inside depressive < liver blood stasis and blood stasis heat relieving excess. And kidney and blood stasis, phlegm and blood stasis and each type is the rest of the various effect on the patient’s cognitive level is relatively obvious,with statistical significance(P<0.05) and kidney and blood stasis and phlegm and blood stasis mutual junction has no obvious difference between the two type, no statistical significance(P>0.05).Conclusion:Traditional Chinese medicine syndromes of carotid atherosclerosis with mild cognitive impairment, with kidney deficiency and blood stasis, phlegm and blood stasis. And the distribution of TCM syndrome types is more complex,often with two kinds of combination of three types of composite syndrome is more common. There was a correlation between age and educational level and the level of cognitive function in patients. Carotid atherosclerosis with TCM syndrome type of mild cognitive impairment to kidney deficiency and blood stasis and phlegm stasis mutual pair of cognitive function in patients with the level of impact is obvious.