The Applied Research Of SWE In Prostate Biopsy And Analyze The Value Of 6 Cores In 6+X Cores Prostate Biopsy

Objective To compare the clinical value of 6+X cores and X cores prostate biopsy guided by transrectal ultrasound(TRUS) in diagnosis of prostate cancer(PCa),to analyze the necessity of 6 cores in the later puncture.Analysis the value of SWE in prostate biopsy. Methods First stage: From April 2014 to October 2015, the 71 patients who were suspected to suffer from PCa and meted for prostate biopsy standards underwent 6+X cores prostate biopsy respectively under the guidance of conventional ultrasound, and analyzed the materials retrospectively. Second stage: From November 2015 to March 2016, the 22 patients who were suspected to suffer from PCa and meted for prostate biopsy standards underwent 6+X cores prostate biopsy respectively under the guidance of conventional ultrasound and SWE, and analyzed the materials retrospectively. Results First stage: All the patients divided into group A and group B according to the pathological results whether is or not PCa, differences in prostate specific antigen(PSA) had statistical significance between the two groups(P<0.05), and differences in age and prostate volume showed no statistical significance between the two groups(P>0.05). All the patients were divided into three subgroups according to PSA level(4ng/ml<PSA≤10ng/ml,10ng/ml<PSA≤20ng/ml,PSA>20ng/ml), statistical analysis of data showed that there were no significant difference in the detection rate of PCa between 6+X cores biopsy and X cores biopsy in the three PSA level subgroups(P>0.05). Second stage: Guiding by conventional ultrasound separately, the detection rate of PCa was 38.10%, the omission diagnostic rate was 20%, the specificity of the diagnosis of PCa was 45.83%, the sensibility was 80%. Guiding by SWE separately, the detection rate of PCa was 42.86%, the omission diagnostic rate was 10%, the specificity of the diagnosis of PCa was 47.83%, the sensibility was 90%. Guiding by both conventional ultrasound and SWE, the detection rate of PCa was 47.62%, the omission diagnostic rate was 0, the specificity of the diagnosis of PCa was 50%, the sensibility was 100%. Statistical analysis of data showed that there were also no significant difference in the detection rate of PCa between 6+X cores biopsy and X cores biopsy in the above three PSA level subgroups guiding by both conventional ultrasound and SWE(P>0.05). Conclusion The application of SWE can improve the detection rate of PCa properly and reduce the missed diagnosis of PCa. Compared to X cores prostate biopsy, 6+X cores TRUS-guided prostate biopsy don’t improve the detection rate of PCa significantly, with the rapid development of various technologies, if the suspicious nodules(X) are very clear, and the detection rate of PCa is basically the same between 6+X cores biopsy and X cores biopsy, the systematic six cores in 6+X cores will be probably cancelled in the near future.