Clinical Study On Relationship Between Different Syndrome Type Of Uyghur Medicine, Plasma Brain Natriuretic Peptide And Left Heart Function Index In Patients With Chronic Heart Failure

Objective: 1.To study the rule of changes between syndrome differentiation type of Traditional Uyghur Medicine, plasma B-type natriuretic peptide and left heart function index(NYHA classify, LVEF) in patients with chronic heart failure(CHF). 2.To research the relationship of changes between syndrome differentiation typ of Traditional Uyghur Medicine, Plasma B-type natriuretic peptide and heart function index( NYHA cardiac classification type, LVEF) in patients with chronic heart failure(CHF). Method: 80 cases who caught chronic heart failure were selected in The Xinjiang Uyghur Autonomous Region Traditional Uyghur Medicine Hospital. After collecting clinical symptoms, signs and related results, all the cases were divided into four groups: Abnormal safra syndrome group, Abnormal khan syndrome group, Abnormal phlegm syndrome group, Abnormal savda syndrome group; The data collected were underwent Chi-square test, One-way ANOVA and linear regression analysis. Results:1.There are obvious correlation among syndrome type of Traditional Uyghur Medicine, the index of BNP and the left heart function index(NYHA cardiac classification type, LVEF) in patients with chronic heart failure. 2.When the type of syndromes are changing among Abnormal safra syndrome group, Abnormal khan syndrome group,Abnormal phlegm syndrome group, Abnormal savda syndrome group, the indexes of BNP and NYHA cardiac classification type increase significantly and the index of LVEF decreases with statistical significance(P<0.05); as forBNP index, there existes obvious difference among the four syndrome types(P<0.01).Compared with syndrome of Abnormal safra, Abnormal khan and Abnormal phlegm the syndrome of Abnormal savda elevates remarkably(P<0.01), while there is no statistical difference between syndrome of Abnormal khan, Abnormal safra and Abnormal phlegm(P>0.05). 3.Different NYHA grades contribute to the changes of BNP and LVEF value significantly(P<0.01 or 0.05). With the increases of NYHA grade, BNP value goes up rapidly and LVEF go down clearly, but the BNP value is no statistical difference between NYHA grade â…¢andâ…£(P > 0.05). 4.The linear regression analysis shows that the correlation between the index of BNP index and LVEF index was negative, but their relationship is not close and we can not use LVEF value to expect BNP value.Conclusion:1.Heart function index can provide reference to classify syndrome differentiation type of Traditional Uyghur Medicine in patients with chronic heart failure(CHF). With the aggravation of type of Traditional Uyghur Medicine, the level of BNP and NYHA grade is developing gradually. 2.With the increase of NYHA grade, the level of BNP elevates correlately while the level of LVEF decreases conversely; the correlation between the index of BNP index and LVEF index was negative, but their relationship is not close and we can not use LVEF value to expect BNP value.