The Clinical Research In The Treatment Of Intestinal Qi Stagnation TyPe Of Slow Transit Consti Pation By Xuanlou Wumo Yinzi

Objective: To observe the clinical efficacy of the treatment of intestinal qi stagnation ty Pe of slow transit consti Pation by Xuanlou Wumo Yinz.Methods: Screening 72 Patients with intestinal qi stagnation ty Pe of slow transit consti Pation, According to the random number table is divided into treatment grou P 36 cases, 36 cases of the control grou P. Treatment grou P was treated with Xuanlou Wumo Yinz., control grou P was treated with Prucalo Pride Succinate Tablets. The course of treatment was 4 weeks. After the end of treatment, The two grou Ps of Patients before and after treatment of consti Pation sym Ptom score, TCM syndrome integral table, the weekly com Plete s Pontaneous bowel movement(SCBM) frequency and the Patient’s quality of life self rating scale(PAC-QOL) scores were com Pared and analyzed.Results: 1.Of 72 Patients in the Process of observation of 5 cases of Personal affairs or out of observation, 5 cases did not require medication is not included in the statistics. Final effective case treatment grou P was 32 cases, 30 cases in the control grou P. There was no significant difference in gender, age, course of disease, sym Ptom score before treatment between the two grou Ps(P > 0.05). 2. Treatment group total effective rate was 84.37%, control group total effective rate was 86.67%.1) constipation symptoms integral change: constipation symptoms before treatment to the total integral treatment group was 10.72 + /- 3.12, 11.03 + /- 3.04 in the control group, treatment group after treatment of 4.63 + /- 3.42, 4.00 + /- 3.46 in the control group(P < 0.05), the comparison between groups(P > 0.05);Review table(2) the doctor of traditional Chinese medicine symptom integral change: before treatment, treatment group was 9.21 + /- 3.13, 8.00 + /- 2.40 in the control group, treatment group after treatment of 2.75 + /- 2.62, 3.90 + /- 3.05 in the control group, integral before and after the treatment significantly decreased(P < 0.05), the comparison between groups(P > 0.05).(3) single TCM symptom integral change: after treatment, the treatment group in abdomen bilges full, belching frequency,irritability, unhappy a few symptoms of the treatment effect is better than the control group(P < 0.05). 3. During the treatment, treatment grou P com Pletely natural defecation(crosscut) more than or equal to 3 times / week Pro Portion is 37.5% and control grou P was 43.3%, grou P com Pared to no significant difference(P > 0.05); the Pro Portion of Patients before and after treatment, the average every week crosscut and increase is more than or equal to 1, the treatment grou P was 59.3% and control grou P was 70.0%, grou P com Pared to no significant difference(P > 0.05). 4. PAC-QOL(consti Pation s Pecific quality of life) before and after the table score com Parison: two grou Ps before and after treatment in the Physiological, social discomfort, anxiety, satisfaction and total score are reduced. There was no significant difference between the two grou Ps(P > 0.05). 5. Safety decision: no serious adverse reactions during the treatment Period, breathing, blood Pressure, body tem Perature, Pulse and other major vital signs were not observed abnormal fluctuations, the treatment and examination before and after treatment were not abnormal. Adverse reactions in the treatment grou P, the incidence of side effect and the incidence of headache and abdominal Pain were less than those of the control grou P, the difference was statistically significant(P < 0.05). 6. Follow-u P com Parison: after 4 weeks, a total of 15 cases of recurrent consti Pation sym Ptoms, including the treatment grou P of 7 cases, the recurrence rate of 8, 25.9% cases of the control grou P, the recurrence rate of 30.7%, the difference between the grou Ps was not statistically significant.Conclusion: Xuanlou Wumo Yinzi can significantly im Prove intestinal qi stagnation ty Pe of slow transit consti Pation sym Ptoms, increase the Patients com Pletely natural frequency of defecation, im Prove the quality of life of Patients. In abdominal swelling, irritability irritability, de Pressed, belching frequently for several TCM sym Ptoms, Xuanlou Wumo Yinzi treatment effect is su Perior to Prucalo Pride Succinate Tablets will benefit Piece, and side effect less.