| Objective To locate the metastatic bone tumors of the spine accurately and distinguish from degenerative bone changes by SPECT/CT fusion imaging.Methods Collection of 100 patients of SPECT/CT fusion imaging who have explicit history of malignancy in different parts of spine, which show a single abnormal radioactivity concentration aggregation in the strove and have a positioning and qualitative statistic.Results Statistics of 100 cases of SPECT/CT fusion imaging reveal that there are 77 cases of spine bone destructive lesions, at the proportion of 77 percent and 23 cases of degenerative bone changes at the percentage of 23.Among them, those who have bone destruction in vertebral body are 43 cases at the ratio of 43 percent, bone destruction in vertebral arch are 30 cases at the percentage of 30,bone destruction in ridge rib-joint are 3 cases at the proportion of 3 percent while there is just one case of bone destruction in transverse at 1 percentage. In the meanwhile, there are 8 cases of vertebral body degenerative bone changes,2 cases of vertebral arch bone degenerative bone changes,10 cases of facet bone degenerative changes and 3 cases of transverse process bone degenerative bone changes, at the percentage of 8,5,10,3, respectively. The sensitivity and specificity of Metastatic tumor of bone diagnosed by SPECT/CT 99mTc-MDP bone imaging in spinal solitary lesions are 97.4% and 86.9%, respectively. Correspondingly, the positive likelihood ratio is 7.43,negative likelihood ratio is 0.029,positive predictive value is 0.961 and negative predictive value is 0.909.Conclusions The abnormal radioactivity concentration aggregations are showed in the patients who have explicit history of malignancy by means of SPECT whole-body bone imaging. The diagnostic accuracy of nuclide bone imaging have been greatly improved for the reason of not only the precise localization of metastatic bone tumors but also distinguishing from degenerative bone changes. |
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