The Clinical Study Of Risk Factors Of Progressing Ischemic Stroke

Objective:To discuss the related risk factors of progressive ischemic stroke,providing the medical advices for the prevention and clinical diagnosis and treatment.Methods:Clinical data of 123 cases of patients with ischemic stroke in the second hospital of Shanxi Medical University neurology from December 2013 to December 2014 were selected,34 patients were progressing ischemic stroke, would be as the progressing group,and the other 89 patients were not progressive ischemic stroke, as the not progress group. A retrospective analysis of two groups of patients with past history(history of high blood pressure,history of diabetes mellitus, history of coronary heart disease, history of stroke), and personal history(smoking history, drinking history), biochemical indicators(fasting blood glucose, D—Dimer, low density lipoprotein cholesterol, high density lipoprotein cholesterol, total cholesterol,triglyceride, homocysteine, high sensitive C- reactive protein, blood uric acid),and neck unstable plaque. Firstly, The related factors of appeal were screened by single factor analysis to the chi square test, the risk of Statistical significance factor as the independent variable by Logistic regression analysis.Results:16 factors between the progressing and not progressing groups were analyzed with chi square test,for P<0.05 has the statistical significant. 7 factors had the significant, they were the history of diabetes, stroke, fasting blood-glucose, D—Dimer, low density lipoprotein cholesterol, homocysteine, unstable carotid plaques, the carotid artery stenosis.To ischemic stroke if progress as the dependent variable, the statistical significance was found by single factor analysis of the independent variable in Logistic regression analysis,Logistic regression analysis: History of diabetes, low density lipoprotein cholesterol high,neck unstable plaques, homocysteine have a significant meaning, and high fasting bloodglucose,D—Dimer and stroke history were not significant meaning.Conclusion:History of diabetes, low density lipoprotein cholesterol high, neck unstable plaque,homocysteine and fasting blood-glucose were the major risk factors for progressive ischemic stroke. In clinical work, active treatment and prevention what has the appeal of risk factors of ischemic stroke patients, reduce the incidence rate of progress of ischemic stroke.