| Objective:Liver tumor resection mainly includes the laparoscopic hepatectomy(LH) and the conventional open surgery which is called open hepatectomy(OH). Because of the complexity of structure and function of the liver, it’s easy to cause liver injury, severe bleeding, etc for patients with liver tumor who were treated by OH, thus aggravated the illness. In recent years, with the continuous development and improvement of LH and a large number of clinical applications and its characteristics of high precision, small traumatic, etc, LH has been gradually used in the treatment of liver tumor resection in clinic, while more clinical data is needed to confirm the feasibility, minimally aggressivity and safety of LH. Through the retrospective study of 80 patients with liver cancer resection in our hospital, and the contrast research of liver tumor patients who were respectively treated with LH and OH in this study, it will provide the basis for the better application of LH in clinic, thus with a new ideas for the treatment of liver tumor patients.Methods:80 patients with liver malignant tumor resection in this hospital since June 2012 to October 2014 were selected, and according to the method of surgical resection they were randomized divided into two groups, 31 cases in the observation group and 39 cases in the control group,the observation group were treated with LH while the control group were treated with OH. The intraoperative indicators(including the operation time, total blood loss, length of incision and blood flow blocking), the recent curative effect(includingdrainage tube indwelling time, start eating time, usage amount of analgesic and postoperative hospital stay), body temperature, liver function, white blood cell count, the rate of neutrophils and immune response were recorded for statistical analysis in the two groups, while the postoperative complications and long-term curative effect were also compared.Results:The operation time in the observation group were obviously longer than it in the control group, but the total blood loss in the observation group were obviously less than it in the control group, and the length of incision in the observation group were obviously shorter than it in the control group. the rate of blood flow blocking occurring of the observation group and the control group were respectively 11.67%(7/60) and 48.33%(29/60),Good effect of LH significantly than the OH group; The drainage tube indwelling time, start eating time and postoperative hospital stay in the observation group were obviously less than the OH group; the usage amount of analgesic in the observation group were obviously less than it in the OH group; After operation, the body temperature, white blood cell count and rate of neutrophils all rised, and the rising in the control group was more obviously(P<0.05), but 3 d after operation, these indicators in the two groups all start to return to normal, but these in the control group was LH group higher than the OH group; The humoral immunity and cellular immunity indicators in the two groups were not obviously different, but the Ig G in the LH group were obviously higher than it in the OH group. The liver function indicators 5 d after operation in the observation group were obviously better than OH group; and the rate of normal liver function in the observation group and the control group were respectively 78.33%(47/60) and 21.67%(13/60), the difference was statistically significant(P < 0.05); the rate of postoperative complications occuring were respectively 19.35%(6/31) and 32.65%(16/39), Both two groups were comparable.Conclusions:LH and OH all have a significant curative effect in the treatment for patients with malignant tumor, but compared to OH, LH has characteristics of mall incision, little trauma,less pain, quick recovery, more significant recent curative effect, etc, thus LH is a therapy method with more feasibility, minimally aggressivity and safety for the treatment of liver cancer and worth popularizatin and application in clinic. |
PDF Full Text Request