Early Rehabilitation Program In Patients Who Were Treated With Acute Percutaneous Coronary Intervention Through Radial Artery After Acute Myocardial Infarction

Objective: To determin the safety and the effect on left ventricular ejection fraction(LVEF) and exercise capacity of early regular cardiac rehabilitation program in patients who were treated with acute percutaneous coronary intervention(PCI) through radial artery after acute myocardial infarction(AMI).Method: A totle of 144 patients who received acute PCI after AMI were divided into rehabilitation group and control group.In rehabilitation group,the patients received tne early cardiac rehabilitation program(6 hours after PCI to start) and were instructed to maintain self exercise in their communities for three months.The control group patients just received the routine nursing.Psychological interwention and health education was carried out and healthy way of life(appropriate diet,no-smoking,etc) was guide for two groups at the same time. Observe the incidence of major adverse cardiac events(angina pectoris after infarction, arrhythmia, heart failure), lower limb venous thrombosis and dysuria of two groups during hospitalization.All the subjects underwent echocardiography at the day after PCI,one month later and three months later.The echocardiography parameter left ventricular ejection fraction(LVEF) was observed and compared. And cardiopulmonary exercise testing(CPET) were evaluated at one and three month later,the Metabolic equivalent(METs) and anaerobic threshold(AT)were mesured and compared.Results:(1)The gender composition ratio, race composition ratio,Smoking composition ratio,age, body mass index(BMI),systolic blood pressure(SBP), diastolic blood pressure(DBP), Fasting blood-glucose, creatine kinase(CK),Creatine kinase isozyme B(CK-MB),total cholesterol(TC), high-density lipoproteincholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and triglyceride(TG) were no difference in two groups(P>0.05);(2)The incidence of major adverse cardiac events were no difference in two groups(P>0.05),but the incidence of lower limb venous thrombosis and dysuria in rehabilitation group was lower than control group(P<0.05).(3)The echocardiography parameter LVEF level of the day after PCI was no statistically significant difference two groups,but after one month and three months,the LVEF level in rehabilitation group was significantly higher than it in control group(P<0.05).(4)In rehabilitation group,after one month and three months,the LVEF level was significantly higher than it at the day after PCI(P<0.05).But in control group,the LVEF level at the day after PCI,one month later and three months later were no difference(P>0.05).(5)After cardiac rehabilitation exercise, the parameters of CPET(AT,METs) at one month later was significantly higher than it at three month later in rehabilitation group(P<0.01),but in control group,the level of AT and METs at oneand three month later were no difference(P>0.05).Conclusion: Active participation in the early cardiac rehabilitation exercise for patients who were treated with PCI after AMI is safe and feasible,and it is conducive to the improvement of heart function and exercise tolerance.