DTI The Study Of Neural Network Between Different Types Of Aphasia

Objective:Movement classifying aphasia patients with diffusion tensor imaging study, discuss different types of aphasia after stroke patients with neural network, for different types of aphasia after stroke patients provide certain theoretical basis for the clinical assessment and rehabilitation.Methods:With German Siemens verio 3.0 T mri machine scanner in 15 patients with aphasia after stroke and 16 cases of normal controls for image acquisition, using Siemens machine own post-processing software to determine the FA and ADC values, data analysis using SPSS17.0software package for analysis research. In motor aphasia in normal group, the pathological changes of the left Broca and the anisotropy of the side mirror(fractional anisotropy, FA),average diffusion coefficient(business, coursing together coefficient, ADC) compares the match t test; Lesion group and control group in the left Broca FA value, ADC values in comparison with independent sample t-test; Think the difference was statistically significant(P < o. 05. In conduction aphasia cases of normal control group, group of Broca area and Wernicke area and the side mirror area of FA and ADC values are compared, and then according to the data for analysis.Results:1. This study by the Peking University first hospital neurology Chinese aphasia examination(ABC) and analysis of the hand, all are right-handed, 7 cases of 11 patients with aphasia motor aphasia, 3 patients with conduction aphasia.2. In the motor aphasia:Normal control group in the bilateral cerebral hemisphere 44 FA value, was no significant difference of ADC values, the results were not statistically significant(P > 0.05).Lesion group and control group on the left side of the FA value, the comparison of ADC values, visible on the left side of the 44 the FA values are lower, compared with the corresponding area of the control group were statistically significant(P < 0.05). But the lesion group compared with the control group on the left side of the ADC values of no statistical significance(P > 0.05).Lesion group of infarction area and the side mirror area FA value, the comparison of ADC values, can be seen the FA value decrease of infarction area, compared with the contralateral mirror area have statistical significance. And the ADC values decline is not obvious of infarction area, statistically insignificant.3 In conduction aphasia:Area and normal control group on the left Broca Wernicke area and the contralateral mirror anisotropy and the comparison of the average diffusion coefficient, visible on the left Broca area, the anisotropy of Wernicke area and the average diffusion coefficient than the contralateral no difference between the image area.Cases of 4 patients with conduction aphasia were left Broca area and Wernicke area and to the side mirror area anisotropy and the comparison of the average diffusion coefficient,visible on the left Broca area, the anisotropy of Wernicke area than the contralateral mirror area reduced, while the average diffusion coefficient changed little, no statistical significance.Conclusion:Of this study were to investigate the diffusion tensor imaging technique in the application of motor aphasia and conduction aphasia, come to the conclusion as follows:1. FA, ADC values in the left hemisphere of the cerebral infarction after motor aphasia,language area FA values decreased ADC values did not change significantly. Therefore, FA value, ADC values transport for motor aphasia research has important significance, also for other types of aphasia research provides certain reference basis.2. By using diffusion tensor imaging observation infarcted white matter fiber and contralateral mirror area, indicating that the white matter fiber beam was reduced significantly lower than the contralateral region, can provide certain theoretical basis for the pathogenesis of aphasia in a variety of clinical treatment and rehabilitation.3. In conduction aphasia left parts of the FA values below the contralateral region lesions near the arcuate fasciculus anterior different manifestations of aphasia caused by posterior segment.