Efficacy Evaluation Of L-carnitine On Acute Cerebral Infarction By MRS

Objective:(1)To study the effect of L – Carnitine to the degree of neural functional disability when applied to different status of acute cerebral infarction, patients for research are divided in two groups: L – Carnitine treatment(treated group) and basic treatment(comparison group);(2) MRS is implemented to observe the change of NAA、Cr、Cho、Lac before and after treatment in L – Carnitine group and basic treatment group, and the functional mechanism of L – Carnitine is also combined to discuss the role of L – Carnitine played in acute cerebral infarction development. Methods:20 acute cerebral infarction patients are randomly devided into two groups: the L – Carnitine group and basic treatment group, both are given fundamental symptomatic treatment, medicine needs be taken in a duration of 14 days, and the two groups are researched in terms of NAA、Cr、Cho、Lac, within and between groups, with MRS in the first and 14 th day in hospital. Meanwhile neural functional defection of patients is also graded. Results:Both the neural functional defection grades of the two groups have become lower, yet the L – Carnitine group declined more significantly. The level of NAA、Cho rise in both two groups, while Lac decreased which appeared more apparently in L – Carnitine group. Conclusion:There is such modification in prognosis of acute cerebral infarction patients when L – Carnitine is applied.