Research On CTnI Of Single-vessel Disease In Patients With ACS Impacted By PCI

Objective: In this study,we treated patients with ACS who had coronary artery single-vessel disease with PCI,then we detected c Tn I before and after PCI,last we analysed correlation between levels of c Tn I and intervention operational factors after PCI.Method: We selected 60 ACS patients with single-vessel disease,testing c Tn I levels before and after PCI,then we detected and recorded various factors of surgical intervention during the PCI surgery.Finally,we analyze it with statistical method.Results: Values of c Tn I is no statistical significant difference in gender,age.There is significant difference between 0 grade group,1 grade group,2 grade group,3 grade group in TIMI flow grade(P<0.05).There is significant difference between <5s group, 5s-10 s group, ≥10s group in balloon dilatation total time(P<0.05).There is significant difference between 1-2 times group, 3 times group and ≥4 times group in balloon dilatation total times(P<0.05).There is significant difference between 14/18 mm group, 24/28 mm group and 33/36 mm group in stent length(P<0.05).Abnormal rate of c Tn I is no statistical significant difference in gender and age(P>0.05). Abnormal rate of c Tn I in TIMI flow grade is 75.0%(0 grade group),30.0%(1 grade group),22.7%(2 grade group)and 10.0%(3 grade group).Abnormal rate of c Tn I in the total time of balloon dilatation is 4.2%( <5s group), 29.2%(5-10 s group), 83.3%(≥10s group). Abnormal rate of c Tn I in the total number of balloon dilatation is 5.3%(1-2 times group), 13.6%(3 times group), 73.7%(≥4 times group). Abnormal rate of c Tn I in stent length is 7.4%(14/18 mm group), 43.3%(24/28 mm group), 100%(33/36 mm group). There is significant difference in some indexs which are TIMI grade, the total time of the balloon(s), the total times of balloon dilation, the length of the stent(mm) released(P<0.05).Conclusions: Patients with ACS who had coronary artery single-vessel disease with PCI,there is a significant relevant between TIMI flow grade, the total time of coronary balloon dilation,the total number of coronary balloon dilation and the length of the stent released during PCI and elevated c Tn I after PCI.