Study On Distribution Regularity TCM Constitution In Patients With Carotid Atherosclerosis Plaque

Objective: Through the investigation of TCM constitutional types on carotid atherosclerotic plaque in patients with carotid atherosclerotic plaque, we analyed of the characteristics of TCM constitution in patients with carotid atherosclerotic plaque,and correlation between TCM constitution and distribution characteristics of gender, age, body mass index, waist hip ratio, blood lipid, blood glucose and body mass, to provide basis for clinical prevention and treatment of Chinese medicine for the treatment of carotid atherosclerotic plaque.Methods: By epidemiological cross-sectional study,we selected the patients with carotid atherosclerotic plaque in strict accordance with inclusion and exclusion criteria.The patients were collected from departments of cardiology, neurology, endocrinology and gastroenterology of Zhengzhou City Hospital of TCM during May 2014 to 2014 December.The survey includes general information,constitution of TCM, body mass index,waist hip ratio,blood lipid,blood glucose and so on.Finally,establish a database and carry on statistical analysis.Results:There are 114 male(55.34%) and 92 female(44.66%) in all 206 patients with carotid atherosclerosis plaques. Among them,101 cases of patients are simple constitution and other 105 cases with composite constitution.The most common of eight constitution types include phlegm dampness,Qi deficiency and phlegm dampness,Qi deficiency and blood stasis,Qi deficiency,blood stasis,mild nature, deficiency of Qi and Yang,Yang deficiency and phlegm dampness,accounting for 68.4% of the total number.Among patients of common constitution types with carotid atherosclerosis plaques,composition of gender and ages has obvious statistical difference(P<0.05).The number of patients with phlegm dampness,Qi deficiency and phlegm dampness,Qi deficiency and blood stasis,blood stasis of BMI are more than 50% over 24.0.BMI of different constitution types are different signifantly by chi square tests and analysis of variance.51.1% patients with waist to hip ratio beyond the normal range boundary.The abnormal waist-to-hip ratio of patients with phlegm dampness,Qi deficiency and phlegm dampness,blood stasis and Yang deficiency and phlegm dampness all excess 50% respectively.The average waist-to-hip ratio of phlegm dampness,Qi deficiency and phlegm dampness are relatively high. Compared with Qi deficiency and mild nature,waist-to-hip ratio of patients with phlem dampness is higher,showing significant difference(P<0.05).The levels of TC,TG,HDL-C,LDL-C are normal for most patients with common constitution types.The average level of TC and TG is the highest in phlegm dampness and blood stasis patients.The differences of different constitution types have statistical significance(P<0.05)..Qi deficiency and phlegm dampness and phlegm dampness constitution have lower HDL-C and higher LDL-C.The LDL-C differences between phlegm dampness and Qi deficiency/Qi and Yang of deficiency showed border statistical differences.(p=0.05, p=0.051).The average levels of fasting glucose in patients of phlegm dampness,blood stasis,Qi deficiency and blood stasis constitution are slightly higher than the normal average.In addition,the difference of fasting glucose between phlegm dampness and deficiency of Qi and Yang also showed border statistical differences(P=0.051).There were no statistically significant differences among other constitutions.Conclusion: 1.The constitution type of patients with carotid atherosclerosis plaques represent single type and complex type,and both types are roughly the same proportion.2.Patients who are Qi deficiency,phlegm dampness and blood stasis are susceptible to carotid atherosclerosis plaques.3 The main types of TCM constitution in male patients with carotid atherosclerosis plaques conclude phlegm dampness,Qi deficiency and phlegm dampness,and Qi deficiency and blood stasis,blood stasis in female patients.Phlegm dampness,Qi deficiency and phlegm dampness occurs mainly in middle-aged patients,while Qi deficiency and blood stasis, Qi deficiency, blood stasis occurs mainly in elderly patients.4.BMI and WHR are highest in patients of phlegm dampness constitution.5 The level of blood lipids in patients with carotid atherosclerosis plaques is closely related to phlegm dampness.6.No significant correlation between blood glucose and constitution in patients with carotid atherosclerosis plaques.