| Coronary heart disease and diabetes are two of the most common internal medicine senile disease, and often in combination, on the basis of diabetic coronary heart disease is to point to in diabetes, concurrent coronary heart disease, modern medicine has developed a lot of drugs to treat these two diseases, traditional Chinese medicine also from thousands of years of practice, summed up many to treat, the formulas of traditional Chinese medicine, western medicine have their own advantages, and now people want to develop a more and more has two advantages of drug treatment, can be more effective and convenient treatment of diabetic coronary heart disease.Objective: Observe the Guan Xin Xiao Ke An Jiaonang in the treatment of syndrome of qi and Yin deficiency and blood stasis two hot type of coronary heart disease(CHD) with sugar or disease clinical curative effect. Comparison before and after treatment of TCM syndrome curative effect, the biggest sports equivalent(Metablic equivalent maxium MET Max), Fasting glucose, Fasting plasma glucose FPG), Fasting insulin, Fasting insulin FINS), insulin sensitive index, insulin sensitivity index(ISI)), insulin resistance index(insulin to hold the index IRI) change, explore Guan Xin Xiao Ke An capsule of qi and Yin deficiency and blood stasis type heat the curative effect of coronary heart disease(CHD) theoretical mechanism.Method:Will be included in the standard of qi and Yin deficiency and blood stasis type hot 48 patients of coronary heart disease, diabetes mellitus, according to the treatment group and control group(n = 24, 1:1 is divided into two groups at random. Treatment group on the basis of conventional western medicine treatment add Guan Xin Xiao Ke An Jiaonang, 4 softgels, 3 times daily, orally after a meal, the controlgroup according to coronary heart disease, diabetes mellitus conventional western medicine treatment, 4 weeks were observed. Through to the control group before and after treatment, two groups respectively compared before and after the treatment, the treatment group before and after treatment, observation of Guan Xin Xiao Ke An Jiaonang on coronary heart disease, diabetes mellitus dialectical to qi and Yin deficiency and blood stasis type heat syndromes in patients with curative effect, the biggest metabolic equivalent athletic flat test, ISI and IRI, fasting glucose, fasting insulin and other indicators.Result: By the above observation, Guan Xin Xiao Ke An Jiaonang can obviously improve TCM symptoms, the improvement of athletic flat test the largest metabolic equivalent, ISIand IRI, fasting glucose, fasting insulin. Syndromes curative effect comparison, the two groups(P<0.05, the treatment group was better than control group; Biggest sports after treatment compared to equivalent, P<0.05,significant differences, fasting glucose, P<0.05, there is significant difference; The two groups after treatment of FPG, FINS, ISI, IRI, P<0.05, all have significant differences.Conclusion: By the above observation, Guan Xin Xiao Ke An Jiaonang can obviously improve TCM symptoms, the improvement of athletic flat test the largest metabolic equivalent, ISI and IRI, fasting glucose, fasting insulin. Syndromes curative effect comparison, the two groups(P<0.05, the treatment group was better than control group; Biggest sports after treatment compared to equivalent, P<0.05, significant differences, fasting glucose, P<0.05, there is significant difference; The two groups after treatment of FPG, FINS, ISI, IRI, P<0.05, all have significant differences. |