Purpura Nephritis In Children Of TCM Syndrome Types And Blood Flow Factor Correlation Study

Objective:Children with purpura nephritis(HSPN) fibrinogen(Fib), D- dimer(D- D),vascular endothelin(ET), calcitonin gene related peptide(CGRP)blood flow factor and the correlation of TCM syndrome types, provide reference basis for clinical medication.Methods:Determination of 70 different TCM syndrome types children with HSPN Fib, D – D,ET, CGRP value, and 23 healthy children as control group.Results:Due to collect gas of children who were not taken blood quantity is less, no statistical significance, therefore the comparison between rule out this card.1. Fib comparison: Blood heat injury syndrome and normal children, wind heat injury syndrome, Yin deficiency with internal three compared were statistically significant(P < 0.01, P < 0.05, P < 0.05); Yin asthenia and internal heat, hot and humid embodiment and normal children compared both are statistically significant(P < 0.05, P < 0.01). Proteinuria compared with simple hematuria, normal children were statistically significant(P < 0.05, P < 0.01).2. D- D comparison: Hot and humid intrinsic certificate and other certificate type, compared to normal children were statistically significant(P < 0.05, P < 0.01). Proteinuria compared with normal children has significant statistical significance(P < 0.01).3. ET comparison: Hot and humid intrinsic card compared with other syndromes have significant statistical significance(P < 0.01); Blood heat injury syndrome Yin asthenia and internal heat compared with statistical significance(P < 0.05); Each type of syndrome compared with normal children have significant statistical significance(P < 0.01). Proteinuria compared with two simple hematuria, and normal children have significant statistical significance(P < 0.01).4. CGRP comparison: Yin internal heat and blood heat injury syndrome, wind heat injury syndrome, hot and humid embodiment in comparison were statistically significant(P < 0.05, P < 0.01, P < 0.05); Each type of syndrome compared with normal children have significant statistical significance(P < 0.01). Normal children compared with simple hematuria and proteinuria have significant statistical significance(P < 0.01).Conclusion:HSPN Fib levels of blood heat injury syndrome in children with the highest, hot and humid intrinsic card D- D the highest level and ET levels, and were higher than normal children; Yin deficiency and internal CGRP level the highest, but is still lower than normal children.