The Influence Factors Of Long-term Prognosis In Patients With Acute Ischemic Stroke Were Analyzed

Objective:Prospective case-control study of the factors affecting the long-term prognosis of patients with acute ischemic stroke.Methods: Collected the cases in neurology intensive care unit the first affiliated hospital of Dalian Medical University during February 2012 to February 2014. 60 acute cerebral infarction case were qualified. Divided into two groups: thrombolytic group and the control group.Thrombolysis group was given intravenous rt- PA(love tong state,Germany boehringer ingelheim company), restructuring organization source of fibrin dissolve enzyme activator.Control group took aspirin antiplatelet therapy immediately when hospitalized.Two groups were checked after 24 h treatment,and reviewed head CT or MRI and conventional treatment, including improve circulation, promote metabolism of brain cells, prevention of complications such as support treatment, etc.Results:1 the influence factors of quality of life analysis:1.1 Single factor analysis of quality of life: age, rt- PA treatment, alcohol, BI,m RS score correlation with SS- QOL scores scores, the difference was statistically significant(P < 0.05 or P < 0. 01).1.2 the quality of life of multiple stepwise regression analysis: BI index size prediction effects of quality of life, there are positive correlation.1.3 the quality of life in all areas of multiple stepwise regression analysis:Drinking on SS- QOL score all the vision of a field effect is remarkable,Rt-PA for SS- QOL score each item of the family roles, activities, self-care ability and a great effect on upper extremity function in four areas.BI index for SS- QOL scores all the energy, the family role, language, self-care ability, social activities, emotion,personality, character, thinking, upper limb function, visual acuity and jobs/work 11 field effect significantly, its influence is the most widespread.2 rt- PA’s impact on long-term prognosis in patients with:2.1 long-term prognosis assessment: the two groups in the two groups of patients with baseline differences under the premise of no statistical significance, two groups of 60 patients with acute cerebral infarction incidence after the 12 months to assess prognosis, BI, m RS thrombolysis group and the control group patients and SS- QOL score difference was statistically significant(P < 0.05).2.2 rt- PA in patients with SS- QOL score each item: the influence of the two groups of patients with baseline differences under the premise of no statistical significance, two groups of 60 patients with acute cerebral infarction in SS- QOL score each item(energy, activities, language, family roles, self-care ability, emotion,personality, social role, thinking, upper limb function, visual acuity, job/work)between the difference is analyzed, the result shows: the two groups of SS- QOL each subtype score in mood, personality, social roles and jobs/work 4 difference was statistically significant(P < 0.05).Conclusions:1 BI index can predict the long-term quality of life in patients with acute ischemic stroke, and the most extensive influence on quality of life.2 Use the rt- PA thrombolysis of acute ischemic stroke patients,in the long-term quality of life, daily life activities ability is better than not thrombolysis patients.3 Use the rt- PA thrombolysis of acute ischemic stroke patients,in the long-term quality of life of emotion, personality, social role and job/work is better than not thrombolysis patients.