| The purpose :Paste to investigate in vitro fertilization- embryo transfer(in vitro fertilization embryo transfer, IVF-ET) diminished ovarian reserve(diminished ovarian reserve, DOR) egg quality, impact and mechanism of clinical pregnancy patients.Methods: 60 patients with diminished ovarian reserve were randomly divided into two groups, the experimental group of 30 patients, two menstrual cycle oral cream party, comparing the experimental group before and after taking the herbal paste symptom scores, serum follicle stimulating hormone basis(FSH), estradiol alcohol(E2) and FSH / LH, serum anti- Mullerian hormone(anti-mullerian hormone, AMH), antral follicle count; 30 cases in the control group not given the drug early intervention and comparison between the experimental and control groups ovarian HCG day endoplasmic artery pulsatility index, resistance index, HCG day dominant follicle number, oocyte maturation date follicular fluid of bone morphogenetic protein-15(bone morphogenic protein 15, BMP-15), the number of egg retrieval, fertilization rate, embryo score and clinical pregnancy.The result : an experimental group after taking the herbal paste kidney deficiency symptoms improved, taking the difference between the pre- cream party and there was a significant(P> 0.05); 2 experimental group received serum basal FSH after Paste, E2, FSH / LH. Compare before AMH and antral follicle count and taking the cream side there was a significant difference(P> 0.05); 3 experimental groups Gn dosage of HCG day between ovarian stromal blood flow PI, RI, the number of dominant follicle, oocyte retrieval days after taking the herbal paste BMP-15, the number of egg retrieval, fertilization rate and quality embryos compared with control group there was a significant difference(P> 0.05);. a significant difference(P> 0.05) 4 experimental groups clinical pregnancy rate in the control group. Conclusion: The cream only improve local ovarian blood flow, affecting egg transforminggrowth factor that regulates the endocrine levels, improve egg quality, improve clinical pregnancy rate. |