| Objective:Discuss with LOTCA homework therapy cognitive assessment scale (second edition) assessment of the disease for the first time in Chinese single lesion of lacunar cerebral infarction patients with early cognitive dysfunction, the characteristics of different pathological changes and each related influence factors of lacunar cerebral infarction effects on cognitive function.Methods:To completely randomized experimental design method. Cases according to the set of lacunar cerebral infarction group and healthy controls and exclusion criteria, selection of from March 2014 to February 2015 in the first affiliated hospital of kunming medical university neurology clinic of lacunar cerebral infarction patients, a total of 78 cases of lacunar cerebral infarction group, with lacunar cerebral infarction patients group of age, gender, education level that matches the patients’ family members, carers, medical personnel and other healthy people 80 cases of healthy controls, the evaluation time is 2 weeks, application homework Loewenstein therapy cognitive assessment scale (second edition) in Chinese from the orientation, visual perception, spatial perception, action, movement, thought operation, attention and concentration to assess aspects such as the research object of cognition. Calculate the total score of each research object scale, each sub-project and secondary component score. Analysis of cases of lacunar cerebral infarction group and healthy controls score if there is a difference. According to the gender, age, education level.Results:Two independent sample t test showed that patients with lacunar cerebral infarction compared with healthy control group early cognitive function, the total score, directional force (apparent motion, visual perception, spatial perception, organization and operation of thinking, attention) component scores and (time orientation, objects recognition, shape recognition, graphics overlap, object recognition, the relationship between body direction, images, aerial, complex geometry, jack puzzle jigsaw puzzle, colorless diamonds, colored squares, broken figure recovery, clock, pictures, images, A, B, logical problem) and secondary component was statistically significant (p< 0.05); 2 early cognitive function in patients with lacunar cerebral infarction associated with infarction area, has nothing to do with different lateral infarction, including early cognitive function in patients with pathological changes of cerebral cortex and basal ganglia region were lower than healthy control group with statistical significance (p< 0.05), the tent of meeting under the lesions (cerebellum and brain stem) site in cognitive function in patients than healthy controls, but without statistical significance (p≥0.05); 3. The Spearman Correlation analysis showed Early cognitive function in patients with lacunar cerebral infarction change with age, education level, high blood pressure, smoking, diabetes, alcohol, hyperlipidemia, and the difference was statistically significant (p< 0.05). Has nothing to do with gender.Conclusion:1 acute lacunar cerebral infarction patients with early cognitive dysfunction, mainly displays in the directional force, visual perception, spatial perception and movement, thinking operation and attention and concentration; 2 early cognitive function in patients with lacunar cerebral infarction associated with infarction area, has nothing to do with different lateral infarction, including early cognitive function in patients with pathological changes of cerebral cortex and basal ganglia region were lower than healthy control group with statistical significance, the tent of meeting under the lesions (cerebellum and brain stem) site in cognitive function in patients than healthy controls, but without statistical significance; 3. The Spearman Correlation analysis showed Early cognitive function in patients with lacunar cerebral infarction change with age, education level, high blood pressure, smoking, diabetes, alcohol, hyperlipidemia, and the difference was statistically significant. Has nothing to do with gender. |