Study Of Serum Measurnment Of B-type Natriuretic Peptide(BNP) And Impedance Cardiography(ICG) In The Differential Diagnosis Of Dyspnea ICU Patients

Background Both serum measurement of B-type natriuretic peptide(BNP) and impedance cardiography(ICG) are used to evaluate patients for heart function in the ICU,but the agreement between the data obtained by these two methods remains uncertain.Objectives Plasma B-type natriuretic peptide(BNP) levels and combined with the impedance cardiography(ICG) to monitor cardiac function in ICU patients, we sought to measure the correlation between BNP levels and ICG measurements in patients presenting to the ICU with dyspnea,and compare the diagnostic accuracy of each method in diagnosing cardiac dyspnea or not.Methods patients with acute dyspnea collected from May 2014 to January 2015 in ICU of our hospital,56 cases of acute dyspnea patients were divided into cardiac dyspnea grope and non-cardiac dyspnea group,according to the diagnostic criteria(Framinghm standard).We performed a prospective observational study of a convenience sample of patients presenting to the ICU with dyspnea,ICG measurement was obtained on each patient and the correlation between BNP level and using GE noninvasive ultrasonic cardiac output montor to measure the ICG parameters CO、CI、SV、SI、ACI、TFC、SVR、SVRI,meanwhile,compare the data of the two groups to determine the diagnosisrusult,enhance the accuracy of the differential diagnosis.To further quantify the diagnostic accuracy of ICG and BNP,we then constructed scatter diagram to compare the data of the two groups.Results Plasma BNP levels in patients with cardiac dyspnea group was higher than non-cardiac dyspnea group(P<0.05),BNP levels in patients with cardiac dyspnea in heart function at different levels between the differences was statistically significant,while the CI was negatively correlated with TFC、SVR was positively correlated with the other parameters no significant correlation.Correlation was significant between BNP and CI、TFC,and correlation was moderate between BNP and SVR.Conclusion Plasma B-type natriuretic peptide(BNP) levels and combined with the impedance cardiography(ICG) has significance in the differential diagnosis of acute dyspnea in ICU patients.