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Preparation And Quality Standards On Tai Yin Tiao Wei Chewing Tablets Health Food

Posted on:2013-11-18Degree:MasterType:Thesis
Country:ChinaCandidate:Y ShiFull Text:PDF
GTID:2284330467967453Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
A required the preparation in health food "Tai yin tiao wei chewing tablets ", dosage form for chewing tablets, anticipate function of gastric mucous membrane has auxiliary for protection. Through the experiment to determine the preparation techniques, set up quality standard, the evaluation function.By "Tai yin tiao wei soup" as the main basis, to determine Semen Coicis, Semen Raphan, Schisandra Chinensis, Radix Ophiopogonis, Radix Plat codonis for raw material.Use Chromatography UV Method total flavonoids the index, optimize the production process are designed way. Through orthogonal test, the research on the influencing factors of extraction, optimizing the extraction process parameters. Select the best extraction process screening the water extraction,alcohol extraction,the ultrasonic extraction method, and the water extraction of total flavonoids has a higher extraction rate. Extraction time, solvent amount have the great effect on the extraction of total flavonoids. The optimum extraction process were as follows: solvent in water, extraction time:twice, extraction time is lh/0.5h, solvent for12times/10times. After optimization the extraction process was stable、reasonable, and has a high extraction rate.To extract respectively by means of ZTC1+1adsorption clarify method for the refined, with clear degree and the flavonoids content as the index, the optimal refining process screening. After refinement the extract is pellucid.With the colour and lustre of chewing flakes, taste, hardness, organization status to index to determine the screening of chewing flakes formulation. The tablets were dry granular liquidity, before parameters such as water content, the pharmacopoeial requirements of check element, each index qualified.Quality standard in the study, tai yin tiao wei chewing tablets of all kinds of medicinal thin layer identify experiment, the control medicinal materials and the product in the corresponding position have shown the same color spots, show color clear, no negative interference, separation effect is good. The detected by HPLC in preparations mustard salt content of alkali thiocyanate, methodology showed that all the index RSD less than2%(n=5).The prevention ethanol acute gastric mucosal injury caused by testing function evaluation, The Tai yin tiao wei chewing tablets have anti-gastric ulcer action.The mechanisms of anti—gastric ulcer might be correlated with reinforcing the defenseability of gastric mucosa.
Keywords/Search Tags:tai yin tiao wei soup, chewing tablets, preparation, quality criterion, functional evaluation
PDF Full Text Request
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